Results 141 to 150 of about 2,439,262 (338)

Stimulation of Adrenergic Beta Receptors by Halothane and its Antagonism by Two New Drugs

, 1969
Alan M. Klide, Mario Penna, Domingo M. Aviado   +2 more
openalex   +1 more source

Antiobesity Medications for Older Adults—the New, the Good, the Bad, and the Unknown

Obesity, EarlyView.
ABSTRACT Objective Obesity affects 42% of older adults, with rates continuing to rise. This a complex condition influenced by non‐modifiable as well as modifiable risk factors. The disease can be treated through modifications to diet, physical activity, and behavior and more recently through antiobesity medications (AOMs) and surgery. Treatment must be
Anna Pendrey, Javier Sevilla‐Martir
wiley   +1 more source

Adrenergic Receptors and the Secretion of Glucagon and Insulin from the Isolated, Perfused Canine Pancreas [PDF]

, 1973
Johan Iversen
openalex   +1 more source

Nectar concentrations of biogenic amines affect bumble bee behavior in a dose‐dependent manner

Oikos, EarlyView.
While foraging, pollinators encounter a wide array of molecules, some of which may influence their internal states and behaviors. Among these, biogenic amines – nitrogenous compounds that serve as essential neuromodulators in animals – have only recently been detected in floral nectar.
Marta Barberis, Daniele Calabrese, David Baracchi, Laura Bortolotti, Flavia Di Cesare, Rosa Ranalli, Laura Zavatta, Massimo Nepi, Marta Galloni, Gherardo Bogo   +9 more
wiley   +1 more source

Identification of cardiac beta-adrenergic receptors by (minus) [3H]alprenolol binding. [PDF]

, 1975
R. Wayne Alexander, L T Williams, Robert J. Lefkowitz   +2 more
openalex   +1 more source

Expanding the Reach of Membrane Protein–Ligand Interaction Studies Through the Integration of Mass Spectrometry and Membrane Mimetics

PROTEOMICS, EarlyView.
ABSTRACT Mass spectrometry (MS) offers robust, label‐free approaches for characterizing ligand–protein interactions through two main strategies: affinity‐based and stability‐based assays. However, their application to membrane proteins (MPs)—a major class of drug targets—has been limited by challenges such as structural complexity, low native ...
Jonathon C. Lambos, Ashim Bhattacharya, Mohammed Al‐Seragi, Franck Duong van Hoa   +3 more
wiley   +1 more source

The role of beta- and alpha-adrenergic receptors on alcohol drinking. [PDF]

Neuropharmacology, 2023
De Oliveira Sergio T, Wean S, Katner SN, Hopf FW.   +3 more
europepmc   +1 more source

Lung‐Derived Small Extracellular Vesicles Containing miR‐15a‐5p/miR‐96‐5p Promote Myocardial Fibrosis in Hypertrophic Cardiomyopathy via Targeting SMAD7

Small, EarlyView.
Small extracellular vesicles (sEVs) are critical regulators of inter‐tissue communication in cardiovascular diseases. In this study, it is found that lung‐derived sEVs enhance cardiac fibroblasts activation and aggravates myocardial fibrosis progression in hypertrophic cardiomyopathy (HCM). sEVmiR‐15a‐5p and sEVmiR‐96‐5p exert this effect via targeting
Minwen Long, Jinpeng Sun, Dongli Zhou, Can Chen, Jiangcheng Shu, Xiaobo Mao, Kunwu Yu, Minglu Liang, Long Chen, Yumei Wang, Min Cheng   +10 more
wiley   +1 more source

Dual‐Targeted Glucose‐Dependent Insulinotropic Polypeptide‐Loaded Photothermal Nanoparticles to Prevent Obesity via Lipolysis and Browning of White Adipose Tissue

Small Science, EarlyView.
Current weight‐loss medications inevitably cause adverse effects such as depression or muscle loss. The developed GIP/ICG@P/R8 NPs specifically promoted energy expenditure by inducing browning, lipolysis and apoptosis of WAT in vitro and in vivo. The results showed a 9.23% weight reduction after 14 days, enhanced insulin sensitivity, improved fatty ...
Ting Xie, Lutang Zhao, Shurui Pei, Kaikai Wen, Sijia Fei, Wan Chen, Zhengyang Li, Long Zhang, Linlin Li, Lixin Guo, Hui Huang, Qi Pan   +11 more
wiley   +1 more source

Characterization of the Human Platelet α-Adrenergic Receptor [PDF]

, 1978
R. Wayne Alexander, Barry Cooper, Robert I. Handin   +2 more
openalex   +1 more source