Results 181 to 190 of about 184,471 (381)

The Chicken Egg Genotoxicity Assay (CEGA): Assessing Target Tissue Exposure and Metabolism in the Embryo‐Fetal Chicken Livers

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The Chicken Egg Genotoxicity Assay (CEGA) is an avian egg‐based model that utilizes the livers of developing chicken embryo‐fetuses to assess the ability of chemicals to produce direct DNA damage. The main goal of the study was to evaluate target tissue exposure and metabolism in the CEGA to assess its suitability as a biologically relevant ...
Yax Thakkar, T. Kobets, Anne Marie Api, J. D. Duan, G. M. Williams   +4 more
wiley   +1 more source

Cell swelling enhances ligand-driven β-adrenergic signaling

Nature Communications
G protein-coupled receptors’ conformational landscape can be affected by their local, microscopic interactions within the cell plasma membrane. We employ here a pleiotropic stimulus, namely osmotic swelling, to alter the cortical environment within ...
Alexei Sirbu, Marc Bathe-Peters, Jothi L. M. Kumar, Asuka Inoue, Martin J. Lohse, Paolo Annibale   +5 more
doaj   +1 more source

Prevention of Epinephrine-Halothane Arrhythmias by Adrenergic α-Receptor Blockade [PDF]

, 1964
John Hess
openalex   +1 more source

Synephrine, a Component of Evodiae Fructus, Constricts Isolated Rat Aorta via Adrenergic and Serotonergic Receptors

Journal of Pharmacological Sciences, 2009
We investigated the effects of Evodiae Fructus and synephrine, one of the components of Evodiae Fructus, on blood vessels. We found that Evodiae Fructus (1 × 10−4 g/mL) had constrictive effects on rat aorta.
Tomoko Hibino, Mitsutoshi Yuzurihara, Yoshio Kase, Atsushi Takeda   +3 more
doaj  

The role of beta- and alpha-adrenergic receptors on alcohol drinking. [PDF]

Neuropharmacology, 2023
De Oliveira Sergio T, Wean S, Katner SN, Hopf FW.   +3 more
europepmc   +1 more source

Kinins, beta‐adrenergic receptors and functional vasodilatation in the submaxillary gland of the cat

, 1968
N. Sheldon Skinner, Marion E. Webster
openalex   +1 more source

Research progress on the mechanisms of pain empathy

Ibrain, EarlyView.
This article is related to the graphical research progress of pain empathy, starting with the description of the pain matrix and mirror neurons. Based on the pain matrix and mirror neurons, pain empathy results from the combined action of brain regions such as the anterior cingulate cortex, insula, prefrontal cortex, and amygdala and regulatory ...
Shuangshuang Liu, Siwei Wang, Yan Yan, Bangyong Qin, Qingxiang Mao, Jie Yuan   +5 more
wiley   +1 more source

Things We Do for No Reason: Failing to consider primary aldosteronism in the initial evaluation of hypertension, hypertensive urgency, and hypertensive emergency

Journal of Hospital Medicine, EarlyView.
Abstract Hypertension is frequently treated as essential hypertension. However, secondary causes of hypertension should be considered, because distinct treatments are used for different causes of hypertension. Primary aldosteronism is considered a candidate for the most common cause of secondary hypertension.
Michael C. Shih, Tessa R. Lavorgna, Prerna Dogra, Christina N. Hirner, Kristen Payne   +4 more
wiley   +1 more source

Associations among sleep quality, cognitive processing therapy, and posttraumatic stress disorder symptoms in a primary care setting

Journal of Traumatic Stress, EarlyView.
Abstract Evidence describing the association between sleep quality and trauma‐focused therapy is mixed. This secondary analysis of a primary care sample examined whether (a) baseline sleep quality moderated posttraumatic stress disorder (PTSD) symptom severity over time across groups receiving different doses of cognitive processing therapy (CPT) and ...
Nicola Park, Julien Rouvere, Erin Chase, Brittany E. Blanchard, Debra L. Kaysen, Rebecca C. Hendrickson, John C. Fortney, Joseph M. Cerimele   +7 more
wiley   +1 more source

Safety and Effect of 12‐Month Ecopipam Treatment in Pediatric Patients with Tourette Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Tourette syndrome (TS) is a chronic neurodevelopmental tic disorder with a considerable quality of life (QOL) burden. Objectives The goal was to determine the long‐term safety, tolerability, and clinical effects of ecopipam, a first‐in‐class dopamine D1 receptor antagonist, for TS.
Donald L. Gilbert, David J.B. Kim, Meredith M. Miller, Sarah D. Atkinson, George B. Karkanias, Frederick E. Munschauer, Stephen P. Wanaski, Timothy M. Cunniff   +7 more
wiley   +1 more source