Results 11 to 20 of about 105,445 (313)

Role of adrenergic receptors in shock [PDF]

Frontiers in Physiology, 2023
Shock is a severe, life-threatening medical condition with a high mortality rate worldwide. All four major categories of shock (along with their various subtypes)—hypovolemic, distributive, cardiogenic, and obstructive, involve a dramatic mismatch ...
Mathew Geevarghese, Krishna Patel, Anil Gulati, Anil Gulati, Anil Gulati, Amaresh K. Ranjan   +5 more
doaj   +4 more sources

ADRENERGIC RECEPTORS IN CORONARY ARTERIES* [PDF]

Annals of the New York Academy of Sciences, 1967
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/72463/1/j.1749-6632.1967.tb41248.x ...
David F. Bohr
openalex   +5 more sources

Deciphering the Role of Adrenergic Receptors in Alzheimer’s Disease: Paving the Way for Innovative Therapies [PDF]

Biomolecules
Neurodegenerative diseases are currently among the most devastating diseases with no effective disease-modifying drugs in the market, with Alzheimer’s disease (AD) being the most prevalent.
Androulla N. Miliotou, Andria Kotsoni, Lefteris C. Zacharia   +2 more
doaj   +2 more sources

Comparative Study of the Effects of Drugs Targeting Adrenergic Receptors on the Early Life Stages of Zebrafish [PDF]

Toxics
Owing to the presence of drugs targeting adrenergic receptors in aquatic ecosystems, considerable attention has been directed towards their environmental distribution and fate in recent decades.
Junsheng Lv, Fengzhu Sun, Zaitian Li, Yueyun Qin, Ruozhu Sheng, Liwei Sun   +5 more
doaj   +2 more sources

Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction

Pharmaceuticals, 2022
This paper proposes the design of combination opioid–adrenergic tethered compounds to enhance efficacy and specificity, lower dosage, increase duration of activity, decrease side effects, and reduce risk of developing tolerance and/or addiction ...
Robert Root-Bernstein
doaj   +1 more source

Ligands of Adrenergic Receptors: A Structural Point of View

Biomolecules, 2021
Adrenergic receptors are G protein-coupled receptors for epinephrine and norepinephrine. They are targets of many drugs for various conditions, including treatment of hypertension, hypotension, and asthma.
Yiran Wu, Liting Zeng, Suwen Zhao
doaj   +1 more source

Co-Evolution of Opioid and Adrenergic Ligands and Receptors: Shared, Complementary Modules Explain Evolution of Functional Interactions and Suggest Novel Engineering Possibilities

Life, 2021
Cross-talk between opioid and adrenergic receptors is well-characterized and involves second messenger systems, the formation of receptor heterodimers, and the presence of extracellular allosteric binding regions for the complementary ligand; however ...
Robert Root-Bernstein, Beth Churchill
doaj   +1 more source

Alpha adrenergic receptors in clinical practice – Present and future

Acta Marisiensis - Seria Medica, 2022
In this review we discuss the adrenergic pathways for alpha 1 and alpha 2 receptors and the current as well as potential future medication targeting these receptors.
Lechsner Patrick, Ban Erika-Gyongyi
doaj   +1 more source

Opposing effects of α2- and β-adrenergic receptor stimulation on quiescent neural precursor cell activity and adult hippocampal neurogenesis. [PDF]

PLoS ONE, 2014
Norepinephrine regulates latent neural stem cell activity and adult hippocampal neurogenesis, and has an important role in modulating hippocampal functions such as learning, memory and mood.
Dhanisha J Jhaveri, Ishira Nanavaty, Boris W Prosper, Swanand Marathe, Basma F A Husain, Steven G Kernie, Perry F Bartlett, Vidita A Vaidya   +7 more
doaj   +1 more source

α1-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition

Frontiers in Pharmacology, 2020
α1-adrenergic receptors are G-Protein Coupled Receptors that are involved in neurotransmission and regulate the sympathetic nervous system through binding and activating the neurotransmitter, norepinephrine, and the neurohormone, epinephrine.
Dianne M. Perez
doaj   +1 more source