Results 91 to 100 of about 12,329 (213)

Elastographic Evaluation of the Adrenal Glands of Dogs With Hypercortisolism

Veterinary Radiology &Ultrasound, Volume 67, Issue 2, March 2026.
ABSTRACT Elastography is a promising technique for assessing tissue stiffness in the adrenal glands of dogs with hypercortisolism (HC). This study compared 30 dogs, 15 of which were healthy (control group) and 15 diagnosed with HC, confirmed by low‐dose dexamethasone suppression test (n = 11) or ACTH stimulation test (n = 4) without prior treatment ...
Fernanda de Paula Sesti, Gabriel Marchiori Gonzaga, Bruno Alberigi   +2 more
wiley   +1 more source

Adrenocortical neoplasia: evolving concepts in tumorigenesis with an emphasis on adrenal cortical carcinoma variants [PDF]

, 2011
Adrenocortical carcinoma (ACC) is a rare, heterogeneous malignancy with a poor prognosis. According to WHO classification 2004, ACC variants include oncocytic ACCs, myxoid ACCs and ACCs with sarcomatous areas. Herein, we provide a comprehensive review of
Ronald R. de Krijger, Thomas G. Papathomas   +1 more
core   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Synchronous aldosterone- and cortisol-producing adrenocortical adenomas diagnosed using CYP11B immunohistochemistry

SAGE Open Medical Case Reports, 2019
Immunohistochemistry with antibodies targeting enzymes responsible for the final conversion steps of cortisol (CYP11B1) and aldosterone (CYP11B2) is gaining ground as an adjunct tool in the postoperative evaluation of adrenocortical nodules.
Adam Stenman, Ivan Shabo, Annica Ramström, Jan Zedenius, Carl Christofer Juhlin   +4 more
doaj   +1 more source

Methylation status of Vitamin D receptor gene promoter in benign and malignant adrenal tumors [PDF]

, 2015
We previously showed a decreased expression of vitamin D receptor (VDR) mRNA/protein in a small group of adrenocortical carcinoma (ACC) tissues, suggesting the loss of a protective role of VDR against malignant cell growth in this cancer type ...
Cappellesso, Rocco, Fallo, Francesco, Fassina, Ambrogio, Guzzardo, Vincenza, Pilon, Catia, Rebellato, Andrea, Sasano, Hironobu, Urbanet, Riccardo   +7 more
core   +4 more sources

Pneumoperitoneum in two cats treated with trilostane for hypercortisolism

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract This report describes two cases of pneumoperitoneum in cats receiving treatment for hypercortisolism and diabetes mellitus. Both cats presented with abdominal distention and lethargy and diagnoses of pneumoperitoneum were radiographically confirmed.
Nicholas James Kelly, Armando Sánchez‐Lara, Mike E. Herrtage, Hannah Wong, Andre Kortum   +4 more
wiley   +1 more source

Atherosclerotic risk factors and complications in patients with non-functioning adrenal adenomas treated with or without adrenalectomy: a long-term follow-up study [PDF]

, 2014
Objective: Despite the increased prevalences of hypertension. type 2 diabetes mellitus (T2DM). hyperlipidemy, and obesity in patients with non-functioning adrenal adenomas (NFAAs), there is a paucity of data on long-term atherosclerotic morbidity as well
Barzon, Bernini, Blanchfield, Bulow, Caplan, Colao, COPELAND, Edit Gláz, Erbil, Fern  ndez-Real, Garrapa, Gross, Ibolya Varga, Judit Tőke, Karolina Feldman, Kinga Karlinger, Károly Rácz, Lazurova, Leibowitz, Libe, Luton, Mantero, McLeod, Midorikawa, Miklós Tóth, Márta Sereg, Reincke, Reincke, Rossi, Seppel, Shen, Sir  n, Szeles, Tanabe, Tauchmanova, Terzolo, Terzolo, Terzolo, Terzolo, Tsagarakis, Tsagarakis, Ágnes Szappanos, Éva Kaszper   +42 more
core   +1 more source

Single‐nucleus and spatial transcriptome reveal adrenal homeostasis in normal and tumoural adrenal glands

Clinical and Translational Medicine
The human adrenal gland is a complex endocrine tissue. Studies on adrenal renewal have been limited to animal models or human foetuses. Enhancing our understanding of adult human adrenal homeostasis is crucial for gaining insights into the pathogenesis ...
Barbara Altieri, A. Kerim Secener, Somesh Sai, Cornelius Fischer, Silviu Sbiera, Panagiota Arampatzi, Stefan Kircher, Sabine Herterich, Laura‐Sophie Landwehr, Sarah N. Vitcetz, Caroline Braeuning, Martin Fassnacht, Cristina L. Ronchi, Sascha Sauer   +13 more
doaj   +1 more source

Hypercortisolism and primary aldosteronism caused by bilateral adrenocortical adenomas: a case report

BMC Endocrine Disorders, 2019
Background Co-existing Cushing’s syndrome and primary aldosteronism caused by bilateral adrenocortical adenomas, secreting cortisol and aldosterone, respectively, have rarely been reported.
Kaiyun Ren, Jia Wei, Qilin Liu, Yuchun Zhu, Nianwei Wu, Ying Tang, Qianrui Li, Qianying Zhang, Yerong Yu, Zhenmei An, Jing Chen, Jianwei Li   +11 more
doaj   +1 more source

Aldosterone-producing adenoma and other surgically correctable forms of primary aldosteronism [PDF]

, 2010
Surgically correctable forms of primary aldosteronism are characterized by unilateral aldosterone hypersecretion and renin suppression, associated with varying degrees of hypertension and hypokalemia. Unilateral aldosterone hypersecretion is caused by an
Laurence Amar, Olivier Steichen, Pierre-François Plouin   +2 more
core   +4 more sources