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Human Pathology, 2018
The tumor microenvironment plays pivotal roles in various human neoplasms. However, that of benign tumor, particularly hormone-secreting endocrine tumors, has remained virtually unknown. Therefore, we firstly attempted to analyze the tumor microenvironment of autonomous hormone-secreting adrenocortical adenomas.
Yasuhiro Nakamura +2 more
exaly +3 more sources
The tumor microenvironment plays pivotal roles in various human neoplasms. However, that of benign tumor, particularly hormone-secreting endocrine tumors, has remained virtually unknown. Therefore, we firstly attempted to analyze the tumor microenvironment of autonomous hormone-secreting adrenocortical adenomas.
Yasuhiro Nakamura +2 more
exaly +3 more sources
Adrenocortical adenoma with rhabdoid features
Pathology Research and Practice, 2006We report a case of an aldosterone producing adrenocortical adenoma with rhabdoid features in a 16-year-old girl. Grossly, the tumor measured 30 mm in diameter and weighed 24 g. Histologically, the tumor was composed of approximately equal parts of tumor cells with rhabdoid features arranged in a solid and trabecular pattern and cells characterized by ...
Pavel Dundr +2 more
exaly +3 more sources
Non-functional adrenocortical adenoma with extensive degeneration
Pathology International, 2003We report a case of non‐functional adrenocortical adenoma of 5.5 × 5.5 × 3.2 cm in size that had an unusual histopathological appearance in two respects. First, the tumor contained small adipose foci with osteogenesis and was suspected of being a myelolipoma based on its appearance on computerized tomography (CT) and magnetic resonance imaging. However,
Yohei Masugi
exaly +3 more sources
Symptomatic Intraspinal Oncocytic Adrenocortical Adenoma
Endocrine Pathology, 2008Most intraspinal neoplasms of epithelial origin are metastases from primary carcinomas. Benign epithelial tumors are rarely found at this site. We here present the case of a 44-year-old woman with a lesion in the cauda equina that fulfilled the radiologic criteria of schwannoma and caused clinical symptoms for 3 years. The excised tumor was composed of
Jens, Schittenhelm +3 more
openaire +2 more sources
A Gonadotropin-Responsive Adrenocortical Adenoma
The Journal of Clinical Endocrinology & Metabolism, 1974ABSTRACT A 49-yr-old virilized woman had a peripheral plasma testosterone (T) concentration of 783–911 ng/100 ml with a normal plasma concentration of androstenedione (A) and normal urinary 17-ketosteroids (17-KS). Plasma LH was below normal and FSH was low normal.
J R, Givens +4 more
openaire +2 more sources
Calcified aldosterone-producing adrenocortical adenoma
Clinical Imaging, 1996We report the first case of benign aldosteronoma of an ordinary size with calcifications. We review the clinical, clinical imaging, histopathological, and laboratory features of aldosterone-producing adrenal adenoma versus carcinoma. We conclude that no single feature is diagnostic, and the full range of data must be considered.
T M, Jelic +11 more
openaire +2 more sources
Mutational landscape of non-functional adrenocortical adenomas
Endocrine-Related Cancer, 2022Adrenal incidentalomas are the most frequent human neoplasms. Recent genomic investigations on functional adrenocortical tumors have demonstrated that somatic mutations in PRKACA and KCNJ5 responsible for the development of adrenocortical adenomas (ACAs) are associated with hypercortisolism and aldosteronism, respectively.
Luming Wu +10 more
openaire +2 more sources

