Journal of Pediatric Surgery Case Reports, 2021 A 3 year old boy with a family history of Li-fraumeni Syndrome presented with a right-sided adrenocortical carcinoma, hepatic, and pulmonary metastases. He underwent eight cycles of chemotherapy with Cisplatin, Etoposide, Doxorubicin and Mitotane. Follow-
Daniel Pasquale Cinelli +4 more
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Mielolipoma adrenal gigante associado à deficiência da 21-hidroxilase: associação não usual simulando um carcinoma adrenocortical secretor de androgênios [PDF]
, 2010 The objective of this study was to describe a case of giant myelolipoma associated with undiagnosed congenital adrenal hyperplasia (CAH) due to 21-hydroxylase (21OH) deficiency.
CASTRO, Margaret de +6 more
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Value of Molecular Classification for Prognostic Assessment of Adrenocortical Carcinoma.
JAMA Oncology, 2019 Importance The risk stratification of adrenocortical carcinoma (ACC) based on tumor proliferation index and stage is limited. Adjuvant therapy after surgery is recommended for most patients.
G. Assié +34 more
semanticscholar +1 more source
European Journal of Haematology, EarlyView.SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley +1 more source
ACTH-producing adrenocortical carcinoma: an exceedingly rare diagnosis
Journal of the Egyptian National Cancer InstituteBackground Adrenocortical carcinoma is a very rare endocrinopathy that has a poor prognosis and is frequently associated with ACTH-independent Cushing’s syndrome.
Miguel Saraiva +5 more
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Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The FEBS Journal, EarlyView.The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Case Reports in Oncology, 2014 Adrenocortical carcinoma is a rare, aggressive malignancy that features a correspondingly poor prognosis. The disease accounts for 0.2% of all malignancies and despite multimodal therapies, its prognosis remains poor, with a mean survival of
Marcos Duarte Siosaki +3 more
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Adrenocortical cancer: late diagnosis of the disease on the example of a clinical case. Case report
Терапевтический архив, 2023 Adrenocortical carcinoma (ACC) is a rare malignant tumor originating in the adrenal cortex and characterized by poor 5-year survival. It occurs with a frequency of 2–4 cases per 2 million in the population. Women are more frequently affected than men and
Evgenia A. Starostina +9 more
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Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/ mTOR axis in metastatic pheochromocytoma/ paraganglioma [PDF]
, 2019 Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar y los autores pertenecientes a la UAMPheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that present variable outcomes.
Alvarez - Escola, Cristina +1 more
core +2 more sources
Outcome of brain metastases from adrenocortical carcinoma: a pooled analysis [PDF]
, 2023 Antonella Turla +13 more
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