Results 91 to 100 of about 34,931 (220)
ABSTRACT Introduction Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy. Recent studies suggest that immune checkpoint inhibitors exhibit antitumor activity in selected ACC patients. Case Presentation We report a case of a 49‐year‐old man with advanced ACC and pulmonary metastasis treated with EDP‐M chemotherapy, followed by ...
Moeto Shimoda +7 more
wiley +1 more source
A 2‐year‐old female golden hamster presented with non‐pruritic alopecia of the hindquarters. Diagnostic imaging and cytological evaluation revealed a unilateral adrenal mass consistent with an adrenocortical tumour, while biochemical analyses suggested corticosteroid secretion.
Mathilde Firmin Billaux +6 more
wiley +1 more source
Preclinical Cushing's syndrome in adrenal incidentalomas [PDF]
Adrenal tumors are usually diagnosed by clinical symptoms of hormone excess. The increasing use of ultrasound and computed tomography results in the detection of a substantial number of incidentally discovered adrenal tumors.
Allolio, B. +5 more
core
Fast‐scanning small‐angle X‐ray scattering of hydrated biological cells
Fast‐scanning small‐angle X‐ray scattering on biological cells in aqueous environments reveals intracellular anisotropy and orientation, and allows for systematic assessment of radiation damage caused by the measurements.Due to their high penetration depth, X‐rays enable us to obtain information from the interior of whole unsliced cells. Scanning small‐
Boram Yu +5 more
wiley +1 more source
Adrenocortical carcinoma: Single center experience
Objective: Adrenocortical carcinoma is an aggressive endocrine malignancy with an annual incidence of 0.5-2 cases per million. The most important factors that determine prognosis are tumor stage at the time of diagnosis and the success of surgery ...
Pınar Şişman +6 more
doaj +1 more source
ABSTRACT The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence‐based medicine techniques and aimed at improvement of the outcomes.
Yoshiaki Kinoshita +116 more
wiley +1 more source
The orphan nuclear receptor Steroidogenic Factor-1 (SF-1, NR5A1) is a critical regulator of development and homeostasis of the adrenal cortex and gonads.
Anna Ehrlund +5 more
doaj +1 more source
novel insights into the genetics and pathophysiology of adrenocortical tumors [PDF]
International audienceAdrenocortical tumors (ACTs) are typically unilateral and can be classified as benign adrenocortical adenomas (ACAs) or malignant adrenocortical cancers (ACCs).
Drougat, Ludivine +3 more
core +7 more sources
Nonfunctioning adrenocortical carcinoma: a study of 12 cases
Background: Adrenal cortical carcinoma is a rare malignant tumor. Several systems were proposed for diagnosis and evaluation of adrenocortical tumors.Weiss system is most commonly used method for assessment of malignancy, but only few studies has applied
S Ghanghoria +3 more
doaj +1 more source
New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells
OBJECTIVES: Transcription Factor 21 represses steroidogenic factor 1, a nuclear receptor required for gonadal development, sex determination and the regulation of adrenogonadal steroidogenesis.
Monica Malheiros França +3 more
doaj +1 more source

