Results 61 to 70 of about 20,049 (168)

Adrenocortical tumors associated with the TP53 p.R337H germline mutation can be identified during child-care consultations

Jornal de Pediatria, 2018
Objective: To evaluate the clinical features associated with adrenocortical hormone overexpression and familial cancer profiling as potential markers for early detection of adrenocortical tumors in children from South and Southeast Brazil.
Maria J. Mastellaro, Raul C. Ribeiro, Antônio G. Oliveira-Filho, Ana L. Seidinger, Izilda A. Cardinalli, Eliana C.M. Miranda, Simone S. Aguiar, Silvia R. Brandalise, José A. Yunes, Antônio A. Barros-Filho   +9 more
doaj   +3 more sources

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

Advanced Science
Adrenal incidentalomas (AIs) are commonly detected endocrine lesions, identified during imaging for unrelated conditions. These lesions exhibit considerable heterogeneity and diverse clinical outcomes.
Meng Wang, Guangmin Zheng, Xiaoyong Hu, Feng Tian, Tuo Li, Zheng Zhang, Kan Gong, Shiwei Chen, Lin Yuan, Yu Qi, Lin Li, Daofu Cheng, Liu Liu, Fuqiang Liu, Yujing Sun, Xiangdong Fang, Ruxing Zhao, Bing Liu, Chao Zhang   +18 more
doaj   +1 more source

TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang, D. Q. Cai, Zhen Zhao, Zhixiang Jian, Mude Shi, Yajin Chen, Jueming Chen, Chunhua Qu, Diankui Cai   +8 more
wiley   +1 more source

Adrenal Primary Ganglioneuroblastoma Presenting in Adulthood: A Case Report

IJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction Ganglioneuroblastoma is a rare neuroblastic tumor derived from embryonic neural crest cells, composed of mature gangliocytes and immature neuroblasts. Although most neuroblastic tumors present in children and commonly involve the adrenal glands, adrenal ganglioneuroblastoma is rare in adults, with only 25 previously reported cases.
Keiichiro Yasuda, Takuji Hayashi, Kentaro Takezawa, Taigo Kato, Koji Hatano, Yoichi Kakuta, Atsunari Kawashima, Eiichi Morii, Norio Nonomura   +8 more
wiley   +1 more source

Genotype analysis of the human endostatin variant p.D104N in benign and malignant adrenocortical tumors

Clinics, 2012
OBJECTIVE: Endostatin is a potent endogenous inhibitor of angiogenesis. It is derived from the proteolytic cleavage of collagen XVIII, which is encoded by the COL18A1 gene. A polymorphic COL18A1 allele encoding the functional polymorphism p.D104N impairs
Beatriz Marinho de Paula Mariani, Ericka Barbosa Trarbach, Tamaya Castro Ribeiro, Maria Adelaide Albergaria Pereira, Berenice Bilharinho Mendonca, Maria Candida Barisson Villares Fragoso   +5 more
doaj   +1 more source

Angiogenesis and Lymphangiogenesis in the Adrenocortical Tumors

Pathology & Oncology Research, 2017
Adrenocortical tumors (ACT) are common adrenal tumors. The majority of ACTs are non-functioning and benign, while adrenocortical carcinomas (ACC) are rare, usually very aggressive and often metastasized when first diagnosed. Our aim was to assess whether blood and lymph vessel density within ACTs correlate with the malignancy character or tumor ...
Sofia S, Pereira, Madalena M, Costa, Susana G, Guerreiro, Mariana P, Monteiro, Duarte, Pignatelli   +4 more
openaire   +2 more sources

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, Volume 293, Issue 13, Page 3991-4013, July 2026.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Histopathological study of adrenocortical masses with special references to Weiss score, Ki-67 index and p53 status

Indian Journal of Pathology and Microbiology, 2015
Background: Adrenal mass present with wide morphological spectrum and clinical manifestation, which can give rise to diagnostic confusion. Proper categorization is essential for individualized treatment.
Gautam Mukherjee, Chhanda Datta, Uttara Chatterjee, Moumita Sengupta, Gaurav Chatterjee, Malay Bera, Subhankar Chowdhury   +6 more
doaj   +1 more source

Tumor adrenocortical:

Oncología, 2007
Hacemos breve revisión sobre Tumores de la Corteza Suprarrenal, sus aspectos macroscópico, microscópico, histopatológico e inmunohistoquímico, Se presenta un caso de Carcinoma de Corteza Suprarrenal, en una paciente de sexo femenino, de 57 años, con antecedentes de hipertensión arterial y sin otras manifestaciones clínicas.
Gabriela Picón C., Araceli Palta G., Pablo Ortega E.   +2 more
openaire   +1 more source