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Adrenocorticotropic Hormone

Handbook of Hormones, 2016
ACTH, which contains 39 amino acid residues, is a peptide hormone secreted from corticotropes in the pars distalis in the pituitary. This peptide is generated from a precursor protein called proopiomelanocortin by posttranslational processing. Release of ACTH is primarily stimulated by corticotropin-releasing hormone produced in the hypothalamus ...
White, Anne, Harno, Erika
semanticscholar   +6 more sources

Cost‐effectiveness of adrenocorticotropic hormone versus oral steroids for infantile spasms

Epilepsia, 2021
To compare the effectiveness and cost‐effectiveness of adrenocorticotropic hormone (ACTH) and oral steroids as first‐line treatment for infantile spasm resolution, we performed a systematic review, meta‐analysis, and cost‐effectiveness study.
Iván Sánchez Fernández   +6 more
semanticscholar   +1 more source

Fulminant vigabatrin toxicity during combination therapy with adrenocorticotropic hormone for infantile spasms: Three cases and review of the literature

Epilepsia, 2020
Vigabatrin (VGB), adrenocorticotropic hormone (ACTH), and prednisone are first‐line treatments for infantile spasms (IS). A recent study reported benefits from the use of combination VGB and hormonal therapy over hormonal treatment alone in IS.
S. Bhalla, K. Skjei
semanticscholar   +1 more source

Modulation of gut microbiota by chlorogenic acid pretreatment on rats with adrenocorticotropic hormone induced depression-like behavior.

Food & Function, 2019
Gut microbiota dysbiosis has been implicated as a vital element in the development or exacerbation of mental disorders, such as major depressive disorder (MDD).
Jing Song   +7 more
semanticscholar   +1 more source

The effect of adrenocorticotropic hormone in epilepsy

The Journal of Pediatrics, 1950
Summary The effects of ACTH, DOC, and cortisone have been studied in six childrenwith epilepsy. In four of these ACTH produced improvement in the EEG or in the clinical condition. DOC had a beneficial effect on the brain wave in one of the two patients given this drug.
Samuel Livingston   +2 more
openaire   +3 more sources

Use of Adrenocorticotropic Hormone in Ophthalmology

Journal of Ocular Pharmacology and Therapeutics, 2020
The ability of the adrenocorticotropic hormone (ACTH) to induce steroidogenesis and upregulate anti-inflammatory processes has long been known. More recently, however, extrasteroidal mechanisms, through which ACTH exerts anti-inflammatory processes, have been described.
Yael Sharon   +2 more
openaire   +3 more sources

Antigenic Properties of Growth Hormone and Adrenocorticotropic Hormone [PDF]

open access: possibleNature, 1952
THE antigenic properties of both purified growth hormone and adrenocorticotropic hormone (ACTH) have been the subject of relatively few investigations. Using growth hormone, Elberg and Li1 have concluded that this hormone is non-antigenic. With adrenocorticotropic hormone both Gordon2 and Chase3, using different techniques, have concluded that ...
A. H. Ennor   +3 more
openaire   +2 more sources

Pulsatile adrenocorticotropic hormone: An overview

Biological Psychiatry, 1997
Adrenocorticotropic hormone (ACTH) is secreted by corticotrophic cells in pulsatile bursts. This paper reviews the extant literature on the phenomenon of pulsatile ACTH after addressing basic issues of hormone pulsatility in neuroendocrine systems. The following themes emerged from reviewing 51 studies measuring plasma ACTH at intervals of 20 min or ...
Adalsteinn Gudmundsson, Molly Carnes
openaire   +3 more sources

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