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Effects of adrenocorticotropic hormone (ACTH) in gout
The American Journal of Medicine, 1950Abstract 1.1. ACTH effected a very rapid and satisfactory response in the local and systemic manifestations of acute gout in seven of eleven cases treated, including one patient refractory to colchicine. ACTH therefore appears to be a useful agent in the therapy of acute gout. In many of these patients, however, ACTH was not convincingly superior to
Alexander B. Gutman, T. F. Yü
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1983
Publisher Summary This chapter provides an overview of human adrenocorticotropic hormone (ACTH), which is a polypeptide of molecular weight 5250, composed of 39 amino acid residues in a single chain with no disulfide cross-linkages. Pituitary synthesis, storage, and release of ACTH is influenced by stress, by circulating levels of corticosteroids, and
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Publisher Summary This chapter provides an overview of human adrenocorticotropic hormone (ACTH), which is a polypeptide of molecular weight 5250, composed of 39 amino acid residues in a single chain with no disulfide cross-linkages. Pituitary synthesis, storage, and release of ACTH is influenced by stress, by circulating levels of corticosteroids, and
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Hereditary adrenocortical unresponsiveness to adrenocorticotropic hormone
The Journal of Pediatrics, 1972Hereditary adrenocortical unresponsiveness to ACTH, a rare form of chronic adrenal insufficiency, was documented in three families. The probands did not respond to prolonged intramuscular ACTH, but they conserved sodium while on a salt-restricted diet. The results of cortisol, aldosterone, deoxycorticosterone, and corticosterone secretory rates in two ...
Gilbert H. Daniels+5 more
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2017
Adrenocorticotropic hormone (corticotropin; ACTH) is a 39 amino acid peptide hormone produced by cells of the anterior pituitary gland and carried by the peripheral circulation to its effector organ, the adrenal cortex, where it stimulates the synthesis and secretion of glucocorticoids and, to a more modest extent, mineralocorticoids and adrenal ...
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Adrenocorticotropic hormone (corticotropin; ACTH) is a 39 amino acid peptide hormone produced by cells of the anterior pituitary gland and carried by the peripheral circulation to its effector organ, the adrenal cortex, where it stimulates the synthesis and secretion of glucocorticoids and, to a more modest extent, mineralocorticoids and adrenal ...
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Adrenocorticotropic Hormone in the Pituitary Gland of the Whale
Nature, 1951A RECENT communication by Boe et al.1 on adrenocorticotropic hormone in the whale prompts us to communicate our own preliminary results on the isolation of this hormone from whale pituitaries. We, however, used the anterior lobe of the whale gland only, and obtained, by Lyons's well-known acid acetone extraction procedure2, from 1 kgm.
Albert Wettstein+2 more
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Adrenocorticotropic Hormone Biotransformation, Clearance, and Catabolism*
Endocrinology, 1978The nature of adrenocorticotropic hormone in circulation has been studied after iv injection of C3H3-methylated ACTH into hypophysectomized adult male rats. The tritium labeling of ACTH by reductive methylation led to no discernible loss of biological activity but resulted in some decrease in immunoreactivity. After iv injection of C3H3-methylated ACTH,
Rodger A. Liddle+3 more
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Equine Veterinary Journal, 2012
REASONS FOR PERFORMING STUDY Pituitary pars intermedia dysfunction (PPID) is a common endocrinopathy, frequently diagnosed via plasma adrenocorticotropic hormone (ACTH) concentrations.
V. Copas, A. E. Durham
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REASONS FOR PERFORMING STUDY Pituitary pars intermedia dysfunction (PPID) is a common endocrinopathy, frequently diagnosed via plasma adrenocorticotropic hormone (ACTH) concentrations.
V. Copas, A. E. Durham
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Radioactive probes for adrenocorticotropic hormone receptors
Biochemistry, 1986Our attempts to develop adrenocorticotropic hormone (ACTH) analogues that can be employed for ACTH receptor identification and isolation began with the synthesis of ACTH fragments containing N epsilon-(dethiobiotinyl)lysine (dethiobiocytin) amide in position 25 to be used for affinity chromatographic purification of hormone-receptor complexes on ...
Frances M. Finn+5 more
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Ectopic Adrenocorticotropic Hormone (ACTH) Syndrome
Archives of Internal Medicine, 1985To the Editor. —In the SeptemberArchives, Sigman and Wallach 1 described a patient with unilateral adrenal hypertrophy and contralateral adrenal atrophy. The authors suggested this was the result of an invasive metastasis to the hypertrophic adrenal that produced ACTH and consequently through hypothalamic feedback caused the contralateral adrenal ...
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ISOLATED ADRENOCORTICOTROPIC HORMONE (ACTH) DEFICIENCY
Acta Pathologica Japonica, 1982The case to be reported is that of a 72‐year‐old woman with isolated adrenocorticotropic hormone (ACTH) deficiency, who complained of anorexia and generalized malaise. The secretions of human growth hormone(HGH), prolactin (PRL), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) were all within normal ...
Isao Morimoto+6 more
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