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INACTIVATION OF ADRENOCORTICOTROPIC HORMONE IN VITRO BY TISSUES*
Endocrinology, 1952The fact that frequent injections of adrenocorticotropic hormon (ACTH) are necessary in order to achieve a maximum physiological or clinical effect, along with the rapid disappearance of adrenocorticotropic activity from plasma which has been demonstrated to occur after intravenous injection of the hormone (Sayers et al 1949; Greenspan el al.
Li Choh Hao, Irving I. Geschwind
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Radioactive probes for adrenocorticotropic hormone receptors
Biochemistry, 1986Our attempts to develop adrenocorticotropic hormone (ACTH) analogues that can be employed for ACTH receptor identification and isolation began with the synthesis of ACTH fragments containing N epsilon-(dethiobiotinyl)lysine (dethiobiocytin) amide in position 25 to be used for affinity chromatographic purification of hormone-receptor complexes on ...
Frances M. Finn +5 more
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Adrenocorticotropic Hormone Biotransformation, Clearance, and Catabolism*
Endocrinology, 1978The nature of adrenocorticotropic hormone in circulation has been studied after iv injection of C3H3-methylated ACTH into hypophysectomized adult male rats. The tritium labeling of ACTH by reductive methylation led to no discernible loss of biological activity but resulted in some decrease in immunoreactivity. After iv injection of C3H3-methylated ACTH,
Rodger A. Liddle +3 more
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Ectopic Adrenocorticotropic Hormone (ACTH) Syndrome
Archives of Internal Medicine, 1985To the Editor. —In the SeptemberArchives, Sigman and Wallach 1 described a patient with unilateral adrenal hypertrophy and contralateral adrenal atrophy. The authors suggested this was the result of an invasive metastasis to the hypertrophic adrenal that produced ACTH and consequently through hypothalamic feedback caused the contralateral adrenal ...
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ISOLATED ADRENOCORTICOTROPIC HORMONE (ACTH) DEFICIENCY
Acta Pathologica Japonica, 1982The case to be reported is that of a 72‐year‐old woman with isolated adrenocorticotropic hormone (ACTH) deficiency, who complained of anorexia and generalized malaise. The secretions of human growth hormone(HGH), prolactin (PRL), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) were all within normal ...
Isao Morimoto +6 more
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The Properties of the Growth and Adrenocorticotropic Hormones
1947Publisher Summary This chapter discusses the properties of the growth and adrenocorticotropic hormones. Biological studies suggest that the metabolic changes resulting from the administration of the growth hormone may involve an entirely different process from that provoked by the adrenocorticotropic hormone.
Herbert M. Evans, Choh Hao Li
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The Mechanism of Action of Adrenocorticotropic Hormone
1969Publisher Summary This chapter discusses the relationship of the structure of adrenocorticotropic hormone (ACTH) to its function and the pathway of adrenal cortical biosynthesis. A series of remarkable achievements in protein chemistry have led to the isolation and purification of ACTH, the determination of its primary structure, and its synthesis ...
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Adrenocorticotropic hormone in the aetiology and regression of neuroblastoma
Medical Hypotheses, 2002Neuroblastoma is predominantly a paediatric neoplasm of the sympathetic nervous system. Despite the aggressive nature of the disease, spontaneous regression is frequently observed in infants diagnosed under the age of 12 months; especially with a specific stage referred to as stage 4s.
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The adrenocorticotropic hormone receptor
Current Opinion in Endocrinology & Diabetes, 2001Armelle Penhoat +2 more
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