Results 161 to 170 of about 1,096,230 (302)

Recent Advances in Reversed-Phase Liquid Chromatography for Therapeutic Oligonucleotide and Conjugate Characterization: From Ion-Pairing to Green Analytical Approaches. [PDF]

Anal Sci Adv
Bui QD, Hewelt-Belka W, Deschrijver T, Gilar M, Eeltink S.   +4 more
europepmc   +1 more source

Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

Advanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu, Yue Xi, Sheng Wang, Ye Chen, Jiajie Yang, Xiaojian Shi   +5 more
wiley   +1 more source

Analysis of porphyrins from serum and the benefit of inert biphenyl columns for liquid chromatography separation. [PDF]

PLoS One
Unnerstall M, Fobker M, Opitz PC, Helmer L, Suero Molina E, König S.   +5 more
europepmc   +1 more source

The In Situ Electrochemical−Chemical Cascade Strategy for Pyruvic Acid Synthesis

Advanced Science, EarlyView.
By employing an “unsaturation−oxygen coordination engineering” strategy, the local coordination environment is regulated to achieve efficient electrochemical synthesis of H2O2. Importantly, an electrochemical−chemical coupled cascade strategy is utilized for the efficient preparation of pyruvic acid via lactic acid oxidation. ABSTRACT Hydrogen peroxide
Xueli Mei, Huawei Zhuo, Yu Liu, Lili Wang, Yudai Huang, Hongtao Xie, Yizhao Li   +6 more
wiley   +1 more source

Reliable Analytical Approach for the Quantification of the Cholesterol Adsorption Capacity of Artichoke Leaves. [PDF]

Foods
Ali S, Ianni F, Cossignani L.
europepmc   +1 more source

Pt‐Regulated Dynamic Cu(0) Regeneration in CuPt Alloy Enables High‐Efficiency Self‐Driven Formaldehyde Fuel Cells for Potassium Formate Production

Advanced Science, EarlyView.
In this work, a Cu30PtX/CF anode material was synthesized to effectively catalyze the electrocatalytic formaldehyde oxidation, and thereby assembled a fuel cell that offered a high open‐circuit potential of 0.94 V and a power density of 34.3 mW cm−2. This work realizes the co‐generation of electrical energy and high‐value‐added chemicals with nearly ...
Hanxu Hou, Yan Zhou, Weixiang Tang, Desheng Sui, Siman Tao, Xiaohan Li, Hui Zhang, Jiawei Qiang, Wenle Li, Jun Zhang   +9 more
wiley   +1 more source

Automated and Highly Efficient Detection of Lignans in Plant-Derived Foods Based on Magnetic Solid-Phase Extraction Combined with UPLC. [PDF]

Foods
Zhu J, Liang N, Wang Y, Liang S.
europepmc   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

Advanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang, Ye An, Na Zeng, Mei‐Cheng Liu, Jian‐Xuan Sun, Xi Gong, Jin‐Zhou Xu, Shao‐Gang Wang, Qi‐Dong Xia   +8 more
wiley   +1 more source

Analytical Methodology for Sensitive Detection of the Antidepressant Drug Duloxetine in Urine Samples Using Riboflavin-Coated Fe₃O₄ Magnetic Particles. [PDF]

ACS Omega
Gargouri R, Ulusoy Hİ, Polat Ü, Yılmaz E, Sarp G, Maalej R, Damak K.   +6 more
europepmc   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source