We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang +19 more
wiley +1 more source
Construction of Sulfhydryl-Amino UiO-66/PVDF Membranes via Morphology Regulation for the Selective Separation of Artesunate. [PDF]
Li K, Wang Z, Meng L, Meng M.
europepmc +1 more source
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Zesheng Chen +13 more
wiley +1 more source
Major compounds in <i>Sandoricum koetjape</i> (Burm.f.) Merr. leaf extract and its corrosion inhibition performance for carbon steel in hydrochloric acid solution. [PDF]
Nguyen NN +7 more
europepmc +1 more source
Strong metal‐support interactions (SMSI) drive the spontaneous segregation of RuPt alloy into Janus nanoparticles on CeO2, spatially partitioning Pt‐rich domains for H2 dissociation and Ru‐rich domains for toluene adsorption. This Janus nanocatalysts yield a turnover frequency of 10 906 h−1 for toluene hydrogenation at 50 °C, which is 6.7 times that of
Xingyu Zhang +5 more
wiley +1 more source
Design and evaluation of novel fluorescein hydrazone derivatives as efficient corrosion inhibitors for carbon steel in acidic media: experimental and computational studies. [PDF]
El Mesky M +13 more
europepmc +1 more source
Photocatalytic Upcycling of Toxic Glyphosate Waste Into Compound Fertilizer for Corn Growth. [PDF]
Jiang Y +5 more
europepmc +1 more source
Thiol-Ene Click-Derived Porous-Layer Open-Tubular Column for Online Purification and Multiplex LC-MS/MS Analysis of Neurotransmitters. [PDF]
Taglioni E +4 more
europepmc +1 more source
Magnetic sugarcane bagasse biosorbent as green sorbents for extraction of carbamates followed by ultra-performance liquid chromatography. [PDF]
Rattanaphonsaen P +6 more
europepmc +1 more source

