Results 161 to 170 of about 6,693,207 (250)

Distinct immune activation patterns in adult-onset Still's disease with fungal infections. [PDF]

Front Immunol
Wu T, Yu Y, Liu X, Chen X, Gu L, Lu L, Guo R.   +6 more
europepmc   +1 more source

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

Advanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr, Reuben Rideaux, Amaya J. Fox, David R. Lightfoot, Jason Tangen, Jason B. Mattingley, Shane E. Ehrhardt   +6 more
wiley   +1 more source

Elevated inflammatory markers are associated with impaired bone health in patients with adult-onset Still's disease: A cross-sectional study. [PDF]

Medicine (Baltimore)
Choi YJ, Kim JW, Jung JY, Suh CH, Kim HA.   +4 more
europepmc   +1 more source

Synchronized Imaging of Hydrogen Peroxide and Hydroxyl Radical in Pyroptosis and Epilepsy

Advanced Science, EarlyView.
A dual‐responsive fluorescent probe, HH, enables synchronized visualization of H2O2 and •OH through spectrally resolved green and red channels. By tracking redox dynamics in pyroptosis and epilepsy models, HH reveals ROS elevation during seizure‐like pathology and supports evaluation of antioxidant and antiepileptic therapeutic interventions.
Yabing Gan, Yuling Xu, Ting Yu, Yang Li, Xin Jiang, Haoyu Jin, Haitao Li, Youyu Zhang, Peng Yin, Jong Seung Kim   +9 more
wiley   +1 more source

Case Report: Adult-onset Still's disease presenting with massive hemorrhagic pericardial effusion without the characteristic rash. [PDF]

Front Med (Lausanne)
Li Y, Wang N, Hu J, Xie C, Yang J, Xu T.
europepmc   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Adult Onset Still's Disease and Autoinflammation

International Journal of Inflammation, 2012
Petros Efthimiou, L. Nandini Moorthy, Clio P. Mavragani, Dimitris Skokos, Bruno Fautrel   +4 more
doaj   +1 more source

Adult-Onset Still's Disease Presenting as Antibiotic-Refractory Sepsis. [PDF]

Cureus
Alnims M, Longi AA, Fazlani M, Mohamed A, Saleh A.   +4 more
europepmc   +1 more source

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

Advanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger, Matthew R. DeWitt, Carly M. Van Wagoner, Claire A. Conarroe, Charles C. Funk, Aaron B. Streit, AeRyon Kim, Richard J. Price, Timothy N. J. Bullock   +8 more
wiley   +1 more source

Adult-onset Still's disease presenting with aseptic meningitis: a case report. [PDF]

Front Immunol
Li XF, Ker A, Liao HL, Liu Y, Wei JC.
europepmc   +1 more source