Results 141 to 150 of about 8,262,084 (314)

On the linguistic implications of context-bound adult-infant interactions [PDF]

, 2004
This poster presents a study of the linguistic information potentially available in adult speech directed to 3-month-old infants. The repetitive nature of the speech directed to young infants and the ecological context of the adult-infant natural ...
Gustavsson, Lisa, Klintfors, Eeva, Lacerda, Francisco, Lagerkvist, Lisa, Marklund, Ellen, Sundberg, Ulla   +5 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Head impact exposure in junior and adult Australian football players [PDF]

, 2018
Tis study measured and compared the frequency, magnitude, and distribution of head impacts sustained by junior and adult Australian football players, respectively, and between player positions over a season of games.
Dempsey, S., Hecimovich, M., King, D., Murphy, M.   +3 more
core   +1 more source

A temporal comparison of BOLD, ASL, and NIRS hemodynamic responses to motor stimuli in adult humans

, 2005
Theodore J. Huppert, Richard D. Hoge, Solomon Diamond, Maria Angela Franceschini, David A. Boas   +4 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Use of high-flow nasal cannula oxygenation in ICU adults: a narrative review

, 2016
Laurent Papazian, Amanda Corley, Dean Hess, John F. Fraser, Jean-Pierre Frat, Christophe Guitton, Samir Jaber, Salvatore Maurizio Maggiore, Stefano Nava, Jordi Rello, Jean-Damien Ricard, François Stéphan, Rocco Trisolini, Élie Azoulay   +13 more
openalex   +2 more sources

Clinical Studies of Escherichia coli O157:H7 Conjugate Vaccines in Adults and Young Children [PDF]

, 2014
Shousun C. Szu, Amina Ahmed
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Multiple sclerosis and amyotrophic lateral sclerosis: is there an association or a red flag? A case report and literature review

BMC Neurology
Background Multiple sclerosis (MS) is an inflammatory disease of the central nervous system that causes damage to the myelin and axons and is caused by genetic or environmental factors.
Raseel Aljthalin, Rawan Albalawi, Atheer Alyahya, Rawabi Alhathlool, Moustafa Alhashemi   +4 more
doaj   +1 more source