Results 171 to 180 of about 6,215,718 (273)

vvECMO can be avoided by a transpulmonary pressure guided open lung concept in patients with severe ARDS

Critical Care, 2019
Philip van der Zee, Dinis Dos Reis Miranda, Han Meeder, Henrik Endeman, Diederik Gommers   +4 more
doaj   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy

Molecular Oncology, EarlyView.
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits, Barbara Andrea Reinoehl, Renate Wagner, Peter Kuess, Franziska Eckert, Anna Sophie Berghoff, Thorsten Fuereder, Rotraud Wieser   +7 more
wiley   +1 more source

Coronavirus disease 2019 in patients with Fontan circulation

International Journal of Cardiology Congenital Heart Disease, 2021
Flavia Fusco, Giancarlo Scognamiglio, Assunta Merola, Michela Palma, Anna Correra, Nunzia Borrelli, Rosaria Barracano, Nicola Grimaldi, Diego Colonna, Emanuele Romeo, Berardo Sarubbi   +10 more
doaj  

Adult-onset Bartter syndrome type IV B with ACTH secreting pituitary microadenoma. [PDF]

J Bras Nefrol
Mathew GG.
europepmc   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Algorithmic fairness audits in intensive care medicine: artificial intelligence for all?

Critical Care, 2022
Davy van de Sande, Jasper van Bommel, Eline Fung Fen Chung, Diederik Gommers, Michel E. van Genderen   +4 more
doaj   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Yaws Circulating in Nonhuman Primates, Uganda and Rwanda. [PDF]

Emerg Infect Dis
Goldberg TL, Owens LA, Nziza J, Muvunyi R, Rothman JM, Omeja P, Chapman CA.   +6 more
europepmc   +1 more source

MicroRNAs in seminal plasma are able to discern infertile men at increased risk of developing testicular cancer

Molecular Oncology, EarlyView.
Male infertility is a known risk factor for the development of testicular cancer. In this paper, we analyzed the expression profile of a microRNA panel by real‐time PCR and validated the results by digital PCR. Experimental and bioinformatics analyses allowed us to identify possible biomarkers able to discern men with a higher risk of developing ...
Carmen Ferrara, Rosalia Battaglia, Angela Caponnetto, Anna Fazzio, Michele Stella, Cristina Barbagallo, Nicolò Musso, Federica Lunelio, Maria Elena Vento, Placido Borzì, Paolo Scollo, Davide Barbagallo, Marco Ragusa, Salvatore Pernagallo, Cinzia Di Pietro   +14 more
wiley   +1 more source