Results 191 to 200 of about 6,215,718 (273)

Aging-Related Changes in Bimanual Coordination as a Screening Tool for Healthy Aging. [PDF]

Geriatrics (Basel)
Shizuka Y, Murata S, Goda A, Sawai S, Fujikawa S, Yamamoto R, Maru T, Nakagawa K, Nakano H.   +8 more
europepmc   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Dynamic assessment of a transition process for patients with diabetes. [PDF]

Health Care Transit
Allan S, Schmitt J, Foster C.
europepmc   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Factors influencing mutual support among older people in China: a cross-sectional study. [PDF]

Front Public Health
Xu L, Lin L, Huang X, Guan A, Cheng L, Zheng Y, Zhang S.   +6 more
europepmc   +1 more source

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

VCO2-derived energy expenditure: do not throw the baby out with the bath water!

Critical Care, 2017
Sandra N. Stapel, Paul W. G. Elbers, Heleen M. Oudemans-van Straaten   +2 more
doaj   +1 more source

Potential evidence of reengagement attempts following interruptions of a triadic social game in bonobos and chimpanzees. [PDF]

PLoS One
Heesen R, Bangerter A, Zuberbühler K, Iglesias K, Rossano F, Guéry JP, Genty E.   +6 more
europepmc   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Sex-specific effects of early-life adversity on adult fitness in a wild mammal. [PDF]

Proc Biol Sci
Drake ED, Ravindran S, Bal X, Pemberton JM, Pilkington JG, Nussey DH, Froy H.   +6 more
europepmc   +1 more source