Results 81 to 90 of about 8,601,286 (363)

Efficacy and Safety of CART Cell Therapy in Aggressive B‐Cell Lymphomas Involving the Gastrointestinal Tract

open access: yesCancer Reports
Objective Currently, chimeric antigen receptor T‐cell (CART) therapy represents a highly effective approach for relapsed/refractory B‐cell lymphomas. However, it also carries treatment‐related risks.
Lixia Ma   +12 more
doaj   +1 more source

Providing Disadvantaged Workers with Skills to Succeed in the Labor Market [PDF]

open access: yes, 2014
Millions of Americans cannot obtain jobs that pay enough to lift them out of poverty. For many, the principal barrier to obtaining these good jobs is their lack of specialized occupational skills increasingly sought by employers.
Irma Perez-Johnson   +2 more
core  

Effects of density experience on mate guarding behavior by adult male Kanzawa spider mites [PDF]

open access: yes, 2008
In the Kanzawa spider mite, Tetranychus kanzawai (Acari: Tetranychidae), adult males guard pre-reproductive quiescent females. I experimentally examined the effects of density experience during development and/or after adult emergence on precopulatory ...
Oku, K.
core   +3 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

A “long-standing” malpositioned pacing lead. Long-term follow-up after extraction

open access: yesMonaldi Archives for Chest Disease, 2018
Transvenous pacemaker (PM) catheters can be unintentionally placed in the left ventricle (LV) during the implantation procedure. An 8-year-old girl was discovered with a malpositioned pm wire, seven years after the implant.
Berardo Sarubbi   +5 more
doaj   +1 more source

Melanophore migration and survival during zebrafish adult pigment stripe development require the immunoglobulin superfamily adhesion molecule Igsf11. [PDF]

open access: yes, 2012
The zebrafish adult pigment pattern has emerged as a useful model for understanding the development and evolution of adult form as well as pattern-forming mechanisms more generally.
Eom, Dae Seok   +7 more
core   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

On the other side of the table: Lessons from the administrator-cum-adult learner [PDF]

open access: yes, 2007
This paper addresses the issue on the changing management and leadership roles of the school administrators as they participate in a tertiary learning program as adult learners.
Abd Majid, Faizah, Ibrahim, Abu Bakar
core  

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