Brockenhurst College: report from the Inspectorate (FEFC inspection report; 43/96 and 88/99) [PDF]
Comprises two Further Education Funding Council (FEFC) inspection reports for the periods 1995-96 and 1998 ...
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Partners with clinical practice: Evaluating the student and staff experiences of on-line continuing professional development for qualified nephrology practitioners [PDF]
The inclusion of online learning technologies into the higher education (HE) curriculum is frequently associated with the design and development of new models of learning.
Hurst, J., Quinsee, S.
core +1 more source
Answering the Calls of "What's Next" and "Library Workers Cannot Live by Love Alone" through Certification and Salary Research [PDF]
Members and staff of the American Library Association (ALA) worked diligently over more than a decade to develop a certification program for public library managers.
Grady, Jenifer
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Welfare Reform: An Issue Overview [PDF]
CRS ReportCRSWelfareReform101403.pdf: 866 downloads, before Oct.
Burke, Vee +1 more
core +5 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Policy and Practice Brief: Medical Continuing Disability Reviews and Related Concepts; A Discussion of Medical CDRs and the Age 18 Redetermination [PDF]
This brief provides an overview of the policies and procedures governing the continuing disability review process within the Social Security Administration.
Sheldon, Jr., James R
core +1 more source

