Results 31 to 40 of about 439,828 (254)
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Best Practices in Assisted Living: Considering Potential Reforms for California [PDF]
Based on a review of assisted living laws of California and 11 other states, California's assisted living policy is significantly out of date. An assisted living resident today is likely to have significant care needs, but California's law in general has
Eric Carlson, Gwen Orloski
core
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Enabling states, capitalising enterprise and confronting the social: issues and implications in researching contemporary social capital and enterprise [PDF]
A key feature of late capitalism continues to be a complex reworking of previous approaches to the relationship between the state and business. This significant shift in the interplay between the public and private sectors has generated such developments
Burton, Lorelle J. +2 more
core +2 more sources
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Education for Institutional Library Service [PDF]
published or submitted for ...
Casey, Genevieve M.
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Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Policy and Practice Brief: Medical Continuing Disability Reviews and Related Concepts; A Discussion of Medical CDRs and the Age 18 Redetermination [PDF]
This brief provides an overview of the policies and procedures governing the continuing disability review process within the Social Security Administration.
Sheldon, Jr., James R
core +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Policy Options for Assisting Child SSI Recipients in Transition [PDF]
The transition process for a child Supplemental Security Income (SSI) recipient nearing the age of 18 can be quite complicated. From a programmatic standpoint, all child SSI recipients have their eligibility redetermined under the adult SSI disability ...
David Wittenburg, Pamela J. Loprest
core

