Reassessing the core of hospitality management education : the continuing importance of training restaurants [PDF]
This paper addresses the role of training facilities within higher education hospitality departments. It identifies a range of historical and contemporary problems associated with these areas and reports on case study research undertaken with four UK ...
Murray, Rowena +6 more
core +4 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
European Union policy on older adult learning : a critical commentary [PDF]
This critical commentary discusses the strengths and lacunae in the European Union’s policy on older adult learning. Late-life learning is deemed as a productive investment on the basis that it not only engenders positive returns of economic growth but ...
Formosa, Marvin
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Continuing Professional Education: Exploring the Experience of Community Nurses Working on a Small Remote Island [PDF]
Qualified nurses require equitable access to continuing professional education (CPE) that is responsive to the needs of learners, employers and most importantly clients.
Lemprière, Julie A
core +3 more sources
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Community education and the conflict of ideals in the history of English adult education movements [PDF]
The main objective of this thesis is to examine a conflict in the field of community education in the 1970s and '80s over whether its efforts should be directed mainly to the intellectual, social and cultural development of the individual (In the ...
Telford, A.E, Telford, Andrena Elisabeth
core
Continuing and higher education [PDF]
This thesis attempts to explain the apparent contradiction between what is said and what is done about providing adult and continuing education in an Australian university.
Martin, John F.
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source

