Results 61 to 70 of about 2,003,365 (292)

Anxiety and depression symptomatology in adult siblings of disabled individuals: The role of perceived parenting, attachment, personality traits and disability types [PDF]

, 2011
Objectives: (1) To ascertain whether adult siblings of disabled individuals are more prone to anxiety and depression symptomatology than a closely matched control group.
O'Neill, Linda P.
core   +2 more sources

The Role of Attachment in Emotional Support Provision in Adult Child–Parent Relationships: A Dyadic Response Surface Analysis

Behavioral Sciences
The adult child–parent relationship is a key source of emotional support across adulthood and older age. This study takes a dyadic, attachment-based perspective to examine how (dis)similarities in attachment orientations between older parents and adult ...
Ella Carasso, Dikla Segel-Karpas, Roi Estlein   +2 more
doaj   +1 more source

The role of both parents’ attachment pattern in understanding childhood obesity

Frontiers in Psychology, 2014
Within the research area on the determinants of childhood obesity, a relatively new approach is the use of attachment theory to explore the mechanisms underlying children’s obesity risk, especially considered as emotion regulation strategies in parent ...
Claudia eMazzeschi, Chiara ePazzagli, Loredana eLaghezza, Giulia eRadi, Dalila eBattistini, Pierpaolo eDe Feo   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Adult attachment and phenomenological characteristics of autobiographical memory [PDF]

, 2008
The aim of the studies undertaken for this thesis was to explore relations between adult attachment and autobiographical memory. Study One investigated how a self-report measure of adult attachment style related to young adults' (N = 211) recall of ...
Tagini, Angela
core  

Attachment and amae in Japanese romantic relationships [PDF]

, 2012
This is the post-print version for the Article. The official published version can be accessed from the link below - Copyright @ 2012 John Wiley & SonsAmae is a Japanese term that refers to an individual’s inappropriate behavior when he/she presumes ...
Marshall, TC
core   +1 more source

The impact of attachment style on posttraumatic stress symptoms and treatment response in survivors of sexual assault

European Journal of Psychotraumatology
Background: Sexual assault (SA) is associated with a high risk of posttraumatic stress disorder (PTSD), and delayed disclosure of SA may exacerbate psychological distress.
Hannah Katznelson, Sarah I. F. Daniel, Sofie Folke, Line Eiby Andersen   +3 more
doaj   +1 more source

Pinpointing Neural Correlates of Attachment in Poly-Drug Use: A Diffusion Tensor Imaging Study

Frontiers in Neuroscience, 2020
An increasing amount of evidence indicates the significance of attachment in the etiology of poly-drug use disorder (PUD). The aim of this study was to investigate associations between PUD and adult attachment in particular, with a focus on white matter (
J. Fuchshuber, J. Fuchshuber, H. F. Unterrainer, H. F. Unterrainer, H. F. Unterrainer, M. Hiebler-Ragger, M. Hiebler-Ragger, K. Koschutnig, I. Papousek, E. M. Weiss, A. Fink   +10 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source