Results 81 to 90 of about 2,003,365 (292)

Attachment style and family presence preference during invasive nursing procedures

Journal of Health Sciences, 2018
Introduction: The attachment style and family presence preference are important during invasive medical procedures. We aimed to analyze the effects of adult attachment styles of the patients which prefer the presence of their family members during the ...
Nurten Kaya, Nuray Turan
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

The Influence of Attachment Styles and Personality Organization on Emotional Functioning After Childhood Trauma

Frontiers in Psychiatry, 2019
Background: Current literature suggests a tenuous link among childhood trauma, personality organization, adult attachment, and emotional functioning in various psychiatric disorders.
Jürgen Fuchshuber, Jürgen Fuchshuber, Michaela Hiebler-Ragger, Michaela Hiebler-Ragger, Adelheid Kresse, Hans-Peter Kapfhammer, Human Friedrich Unterrainer, Human Friedrich Unterrainer, Human Friedrich Unterrainer   +8 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Coping, attachment style and resilience: the mediating role of alexithymia

Mediterranean Journal of Clinical Psychology, 2018
Literature show that the presence of an insecure attachment is at the root of a difficulty in affect regulation and of the implementation of dysfunctional coping and resilience strategies.
Giuseppe Craparo, Paola Magnano, Maria Valentina Zapparrata, Alessio Gori, Giulia Costanzo, Ugo Pace, Monica Pellerone   +6 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The Relationship between Perceived Parenting Behaviors, Adult Attachment Styles, Fear of Self, and Severity of Obsessive-Compulsive Disorder [PDF]

Egyptian Journal of Health Care
Background: Obsessive-compulsive disorder OCD is a serious psychiatric condition characterized by obsessions and repetitive compulsions. Nurses have a challenge to provide evidence-based care by identifying risk factors that exacerbate the symptoms and ...
Alshymaa Mohamed Abdel Tawab, Shymaa Mahmoud Zedan Abdelhai, Aya Mohamed Hussein Abdallah, Basma Elsayed Mohamed Othman   +3 more
doaj   +1 more source

Adult attachment representations, parental responsiveness, and infant attachment: A meta-analysis on the predictive validity of the Adult Attachment Interview.

Psychological Bulletin, 1995
About a decade ago, the Adult Attachment Interview (AAI; C. George, N. Kaplan, & M. Main, 1985) was developed to explore parents' mental representations of attachment as manifested in language during discourse of childhood experiences. The AAI was intended to predict the quality of the infant-parent attachment relationship, as observed in the Ainsworth
openaire   +3 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source