Results 61 to 70 of about 1,014,159 (263)

Learning of Catholic theology in the digital age

HTS Teologiese Studies/Theological Studies, 2019
This article focuses on the intersections between theological knowledge and the use of the Internet to access study resources for students studying Catholic theology at tertiary institutions.
Lelo J. Ngumba, Stephen Mutula, Katherine Arbuckle   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

EFFECTS OF GLOBAL LABOR MARKET TRENDS ON THE CONTENT OF PROFESSIONAL TRAINING OF FUTURE IT MANAGERS

Інформаційні технології і засоби навчання, 2019
The article outlines key trends in the global labor market and Ukraine’s labor market, describes the role of the information technology industry in the global economy and the economy of Ukraine, and establishes the mutual influence of the labor market ...
Larysa B. Lukianova, Olga V. Banit, Tetiana V. Goretko   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Effect of a cognitive behavioural intervention on depression reduction among community-dwelling adult learners in Nigeria: Implications for adult education administration

Journal of International Medical Research, 2020
Objective The study objective was to determine the effect of a cognitive behavioural intervention (CBI) on depression among community-dwelling adult learners in Nigeria. Methods This was a 10-week randomized control trial.
Linus Okechukwu Nwabuko, Ann Ebere Okechukwu, Eberechukwu Charity Eneh, Georgina Chinagorom Eze, Favour Okon Eseabasi   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Adults who learn online: Exploring the online learning readiness of nontraditional undergraduate students in a Ghanaian university

International Journal of Educational Research Open
Despite the growing population of non-traditional (mature) students in online learning programmes in universities across the world, less is known about the online learning readiness of this unique category of students.
David Addae, Ellen Abakah, Delali Amuzu
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The Role of the ‘Post Graduate Diploma in Secondary School Teaching’ Program in Improving the Quality of Teaching in Eastern Ethiopian Secondary Schools

Multidisciplinary Journal of School Education, 2017
This study dealt with the role of the Postgraduate Diploma in Secondary School Teaching (PGDT) program in improving the quality of teaching in Eastern Ethiopian secondary schools.
Sisay Wondemetegegn, Anwar Ahmed, Tamrat Zelalem   +2 more
doaj