The tyrosine kinase inhibitor sunitinib affects ovulation but not ovarian reserve in mouse: A preclinical study [PDF]
, 2016 The aim of the study was to evaluate ovarian toxicity of tyrosine kinase inhibitor (TKI) sunitinib, since only scarce data are available on gonadal function after this treatment.
Bernard, V. (Valérie) +7 more
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Wnt5a Signaling in Normal and Cancer Stem Cells. [PDF]
, 2017 Wnt5a is involved in activating several noncanonical Wnt signaling pathways, which can inhibit or activate canonical Wnt/β-catenin signaling pathway in a receptor context-dependent manner.
Kipps, Thomas J +2 more
core +2 more sources
Cancer overturned: Endometrioma mimicking granulosa cell tumor and the importance of FOXL2 analysis
Gynecologic Oncology Reports, 2019 Background: Various ovarian neoplasms may show histological findings that are morphologically indistinguishable from adult granulosa cell tumor (AGCT).
Emily R. Rosen +3 more
doaj +1 more source
Identification and characterization of miRNAs expressed in the bovine ovary [PDF]
, 2009 Background MicroRNAs are the major class of gene-regulating molecules playing diverse roles through sequence complementarity to target mRNAs at post-transcriptional level.
Tholen Ernst +7 more
core +2 more sources
The molecular mechanism of ovarian granulosa cell tumors
Journal of Ovarian Research, 2018 Over these years, more and more sex cord-stromal tumors have been reported. Granulosa cell tumor (GCT) is a rare tumor in ovaries, accounts for 2% to 5% of ovarian cancers.
Jiaheng Li +3 more
doaj +1 more source
Journal of Medical Case Reports, 2017 Background Among classes of ovarian tumor, granulosa cell tumors are the least common. In approximately 10% of cases of granulosa cell tumor, androgen will be secreted which will present with hirsutism and hyperandrogenemia.
Mulat Adefris, Elfalet Fekadu
doaj +1 more source
Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]
, 1987 To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F. +4 more
core +1 more source
A case of adult granulosa cell tumor presenting as thoracic lesions. [PDF]
Gen Thorac Cardiovasc Surg Cases, 2023 Suzuki K +8 more
europepmc +1 more source
Ruptured Granulosa Cell Tumor of the Ovary as a Cause of Acute Abdomen in Postmenopausal Woman
Case Reports in Oncological Medicine, 2012 Acute abdomen with hemoperitoneum is a very rare entity in postmenopausal women due to gynecologic conditions. A 54-year-old, postmenopausal woman was brought to emergency department with severe abdominal pain. Physical examination revealed acute abdomen
Tufan Oge +4 more
doaj +1 more source
Unusual presentation of adult granulosa cell tumor. A case report and review of the literature. [PDF]
Int Cancer Conf J, 2023 Oqbani K, Mouhoub M, Abbaoui S.
europepmc +1 more source