Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology [PDF]
International audienceBackground : The prostaglandin D2 (PGD2) pathway is involved in numerous biological processes and while it hasbeen identified as a partner of the embryonic sex determining male cascade, the roles it plays in ovarian functionremain ...
Andalib Farhat +4 more
core +2 more sources
Extracellular vesicles (EVs) mediate intercellular and interorgan communication during both physiological and pathological conditions. EVs include exosomes, ectosomes, and apoptotic bodies and contain bioactive molecules. EVs are delivered to proximal cells or can travel in bodily fluids and reach distant organs, where they trigger a response from the ...
Michela Saviana +4 more
wiley +1 more source
Roles of binding elements, FOXL2 domains, and interactions with cJUN and SMADs in regulation of FSHβ. [PDF]
We previously identified FOXL2 as a critical component in FSHβ gene transcription. Here, we show that mice deficient in FOXL2 have lower levels of gonadotropin gene expression and fewer LH- and FSH-containing cells, but the same level of other pituitary ...
Barakat, Nermeen H +7 more
core +1 more source
VGF changes during the estrous cycle: a novel endocrine role for TLQP peptides? [PDF]
Although the VGF derived peptide TLQP-21 stimulates gonadotropin-releasing hormone (GnRH) and gonadotropin secretion, available data on VGF peptides and reproduction are limited.
Brancia C +4 more
core +3 more sources
Adult-type granulosa cell tumor of the testis: report of a case and review of literature
Granulosa cell tumors is classified into juvenile and adult types and comprise less than 5% of ovarian tumors in women and are much rarer in men which only 45 have been previously reported.
Meriem Elbachir +8 more
doaj +1 more source
A rare case of virilizing adult granulosa cell tumor
A twenty eight year old lady, married for two years with no issue, presented at Western Regional Hospital Pokhara on 8th July, 1999 with a history of amenorrhea for 1½ years, lump abdomen 1 year, hoarseness of voice for 1 year and signs of hirsutism for ...
Kaveeta Dawaka +4 more
doaj +1 more source
PDGFB as a vascular normalization agent in an ovarian cancer model treated with a gamma-secretase inhibitor [PDF]
Ovarian cancer is the fifth leading cause of cancer-related deaths in women. In the past 20 years, the canonical types of drugs used to treat ovarian cancer have not been replaced and the survival rates have not changed.
Abramovich, Dalhia Nurit +7 more
core +1 more source
The global effect of follicle-stimulating hormone and tumour necrosis factor α on gene expression in cultured bovine ovarian granulosa cells [PDF]
Background Oocytes mature in ovarian follicles surrounded by granulosa cells. During follicle growth, granulosa cells replicate and secrete hormones, particularly steroids close to ovulation.
Glister, Claire +4 more
core +2 more sources
Peritoneal washing cytology in an adult granulosa cell tumor: A case report and review of literature
Adult-type granulosa cell tumors (AGCT) account for 1-2% of all ovarian tumors and 95% of granulosa cell tumors. In AGCT, at the time of peritoneal washing, tumor cells are rarely seen to exfoliate and FIGO stage is raised from IA/IB or IIA/IIB to stage ...
Alev O Atilgan +3 more
doaj +1 more source
Immunohistochemical detection of macrophage migration inhibitory factor in fetal and adult bovine epididymis: Release by the apocrine secretion mode? [PDF]
Originally defined as a lymphokine inhibiting the random migration of macrophages, the macrophage migration inhibitory factor (MIF) is an important mediator of the host response to infection.
Agarwal A. +57 more
core +1 more source

