Neonatal exposure to xenoestrogens impairs the ovarian response to gonadotropin treatment in lambs [PDF]
, 2015 Bisphenol A (BPA) and diethylstilbestrol (DES) are xenoestrogens which have been associated with altered effects on reproduction. We hypothesized that neonatal xenoestrogen exposure affects the ovarian functionality in lambs.
Belmonte, Norberto Miguel +8 more
core +2 more sources
Circulating levels of TNF-related apoptosis inducing-ligand are decreased in patients with large adult-type granulosa cell tumors-implications for therapeutic potential [PDF]
, 2016 Targeted treatments are needed for advanced adult-type granulosa cell tumors (AGCTs). We set out to assess tumor tissue and circulating levels of TNF-related apoptosis-inducing ligand (TRAIL), a promising anti-cancer cytokine, in patients affected by ...
Farkkila, Anniina +6 more
core +1 more source
Three Different Ways to Miss a Granulosa Cell Tumor – A Lesson to be Learne
Asian Pacific Journal of Cancer Care, 2021 Granulosa cell tumours (GCTs) account for approximately 70% of malignant sex-cord stromal tumors but are still uncommon and comprise only 2–5% of all ovarian neoplasms. They are classified as adult and juvenile GCTs.
Neethu Puthalon Kunnath +2 more
doaj +1 more source
Effects of an inhibitor of the gamma-secretase complex on proliferation and apoptotic parameters in a FOXL2-mutated granulosa tumor cell line (KGN). [PDF]
, 2013 Ovarian granulosa cell tumors (GCTs) represent 3%-5% of all ovarian malignancies. Treatments have limited proven efficacy and biologically targeted treatment is lacking.
Abramovich, Dalhia Nurit +5 more
core +2 more sources
Juvenile Granulosa Cell Tumors of the Testis: A Clinicopathologic Study of 70 Cases with Emphasis on Its Wide Morphologic Spectrum [PDF]
, 2015 The clinical and pathologic features of 70 juvenile granulosa cell tumors (JGCTs) of the testis are presented. The patients were from 30 weeks gestational age to 10 years old; 60 of 67 (90%) whose ages are known to us were 6 months old or younger.
Cornejo, Kristine M. +3 more
core +1 more source
Renal metastasis of ovarian granulosa cell tumor
IJU Case Reports, 2022 Introduction We would like to present a rare case of metastatic renal tumor. Case presentation A 60‐year‐old woman presented to our department with a left renal tumor.
Kyo Togashi +8 more
doaj +1 more source
Familial Occurrence of Adult Granulosa Cell Tumors: Analysis of Whole-Genome Germline Variants [PDF]
Cancers, 2021 Adult granulosa cell tumor (AGCT) is a rare ovarian cancer subtype, with a peak incidence around 50–55 years. Although AGCT can occur in specific syndromes, a genetic predisposition for AGCT has not been identified. The aim of this study is to identify a genetic variant in families with AGCT patients, potentially contributing to tumor evolution.
Joline F. Roze +10 more
openaire +4 more sources
Characteristics and outcome of recurrence in molecularly defined adult-type ovarian granulosa cell tumors [PDF]
, 2016 Objective. Adult-type ovarian granulosa cell tumors (AGCTs) have an unpredictable tendency to relapse. In a carefully validated patient cohort, we evaluated the prognostic factors related to AGCT recurrence. Methods.
Bryk, Saara Susanna +7 more
core +1 more source
Enxtraoviarian granulosa cell tumor: a case report
The Pan African Medical Journal, 2016 Extraovarian granulosa cell tumor (GCT) is a very unusually tumor, assumed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge.
Saad Rifki Jai +4 more
doaj +1 more source
Granulosa cell tumor of testis: Clinicopathological correlation of a rare tumor
Indian Journal of Pathology and Microbiology, 2014 Background: Granulosa cell tumor of testis is a rare tumor accounting for less than 4% of adult testicular tumors though they account for nearly 30% of childhood testicular tumors.
Swapnil Ulhas Rane +4 more
doaj +1 more source