Results 51 to 60 of about 7,376,843 (182)

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo, Natanael Vaz Crisóstomo Peixoto, Paula Soares Nakamura, Cecília Müller Wodzik, Lucas Ribeiro Maia dos Santos, Fábio Vieira de Andrade Borges, Lara Cândida de Sousa Machado, Jéssica Gardone Vitório, Renata Mazaro e Costa, Mônica Rodrigues Ferreira Machado, Walter Dias Júnior   +10 more
wiley   +1 more source

Prognostic factors in adult granulosa cell tumor of the ovary

Saudi Medical Journal, 2009
OBJECTIVE: To determine the clinicopathologic prognostic factors in adult granulosa cell tumors (GCTs) of the ovary. METHODS: This retrospective study was carried out over a period of 10 years (1995-2005) in the Gynecology Department of Shengjing Hospital, China Medical University, Shenyang, China.
Wei, Li, Xin, Wu, Changqing, Fang, Jiafei, Yao, Yi, Guo, Shulan, Zhang   +5 more
openaire   +2 more sources

Adult type granulosa cell tumor of the testis with a heterologous sarcomatous component: case report and review of the literature [PDF]

, 2014
Adult testicular granulosa cell tumors are rare sex cord- stromal tumors of which only 45 have been previously reported. As compared with their ovarian counterparts, these tumors may follow a more aggressive course because the proportion of malignant ...
Gregor Mikuz, Sabrina Schöne, Mikuz, Gregor, Robert Stoehr, Arndt Hartmann, Schubert, Thomas E. O., Hartmann, Arndt, Schöne, Sabrina, Thomas EO Schubert, Mathias Löbelenz, Stoehr, Robert, Löbelenz, Mathias   +11 more
core   +1 more source

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

Pediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang, Yan Fu, Xu Huang, Qitong Guo, Xiangqin Zheng, Shengde Wu, Lianju Shen, Guanghui Wei   +7 more
wiley   +1 more source

Clinicopathologic assessment of patients with ovarian granulosa cell tumor in a tertiary medical center

, 2022
Objectives: To evaluate the clinic-pathological characteristics and management of adult granulosa cell tumor in a university ...
SÖZEN, IŞIK, Oge, Tuf An, KAVAK CÖMERT, DUYGU, ÇAKMAK, YUSUF   +3 more
core  

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Adult Type Testicular Granulosa Cell Tumor: Case Report and Review of the Literature

, 2006
Granulosa cell tumors represent a special group of the so-called sex cord-stromal tumors of the gonads, and are divided into 2 histological types: adult and juvenile.
G. Annunziata, V. Mancini, M. Battaglia, F.P. Selvaggi, G. Lucarelli, S. Palazzo, P. Ditonno, S. Trabucco   +7 more
core   +1 more source

Inhibin βB Mediates Oligotrophic Adaptation via Regulating Muscle Satellite Cell Proliferation and Differentiation in Schizopygopsis younghusbandi

Integrative Zoology, EarlyView.
① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption. ② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.
Weiqiang Li, He Gao, Chaowei Zhou, Luo Lei, Junting Li, Chao Ma, Zitu Ma, Mengwei Yao, Kexin Ma, Yunpeng Xiang, Yan Zhou, Yongrui Lu, Da Ji, Minghong Wei, Luohao Xu, Zhaofang Han, Haiping Liu   +16 more
wiley   +1 more source

Granulosa cell tumor of the ovary and antecedent of adjuvant tamoxifen use for breast cancer

World Journal of Surgical Oncology, 2010
Background Adult granulosa cell tumor associated with antecedent use of tamoxifen as adjuvant hormonotherapy for breast cancer is rare. The pathogenesis of this occurrence remains difficult to explain.
Abahssain Halima, Kairouani Mouna, Gherman Robert, M'Rabti Hind, Errihani Hassan   +4 more
doaj   +1 more source