Results 61 to 70 of about 7,376,843 (182)

Adult Type Granulosa Cell Tumor Causing Precocious Pseudopuberty in a 6 Year-old Girl

open access: yes, 2003
Malignant ovarian tumors are responsible for 2-3% of all cases of precocious pseudo-puberty (PP) in girls. The most common forms of ovarian tumors presenting as PP are the granulosa cell tumors (GCT).
Adal, E   +12 more
core   +1 more source

Wt1 Is Required for the Regression of Müllerian Ducts in Male Mice by Inducing Wif1 and Osx Expression

open access: yesCell Proliferation, EarlyView.
Wt1 expressed in the MD mesenchyme promotes MD regression by inducing Wif1 and Osx transcription. In male mice, mesenchyme‐specific inactivation of Wt1 results in MD retention. ABSTRACT In mammals, Müllerian ducts (MDs) are the precursors of the female reproductive tract which regress in males during embryonic development.
Min Chen   +12 more
wiley   +1 more source

Late retroperitoneal recurrence of adult-type ovarian granulosa cell tumors: Two case reports and literature review

open access: yesScience Progress
Adult-type ovarian granulosa cell tumors are rare low-grade malignancies characterized by late recurrence and atypical clinical manifestations. This study reports two cases of recurrent adult-type ovarian granulosa cell tumor with distinct timelines and ...
Yutao Wang   +3 more
doaj   +1 more source

Clinical and surgical findings in a mare with unilateral ovarian fibroleiomyoma and adhesions

open access: yesEquine Veterinary Education, EarlyView.
Summary This case report describes the clinical presentation, ultrasonographic findings, surgical management and outcome of a 7‐year‐old Warmblood mare presented for recurrent colic, weight loss and poor performance. Rectal palpation identified a firm mass in the left caudal abdomen, which appeared on ultrasonography as a large, fluid‐filled, cyst‐like
N. Scilimati   +8 more
wiley   +1 more source

Retroperitoneal nodal metastasis in primary adult type granulosa cell tumor of the ovary: Can routine lymphadenectomy be omitted?

open access: yes, 2017
Objective: To investigate the incidence of retroperitoneal lymph node metastasis among patients with primary adult type granulosa cell tumor (AGCT) of the ...
Oguzhan Kuru   +15 more
core   +1 more source

TERT promoter mutation in adult granulosa cell tumor of the ovary [PDF]

open access: yesModern Pathology, 2018
The telomerase reverse transcriptase (TERT) gene is highly expressed in stem cells and silenced upon differentiation. Cancer cells can attain immortality by activating TERT to maintain telomere length and telomerase activity, which is a crucial step of tumorigenesis. Two somatic mutations in the TERT promoter (C228T; C250T) have been identified as gain-
Pilsworth, Jessica A.   +25 more
openaire   +4 more sources

Mapping the omics landscape for peri‐implant diseases: A scoping review

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng   +5 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

[Leydig cell, Sertoli cell and adult granulosa cell tumors].

open access: yesDer Pathologe, 2017
According to the World Health Organization (WHO) classification Leydig cell tumors, Sertoli cell tumors and granulosa cell tumors of the testes belong to the group of sex cord-stromal tumors. These tumors most frequently occur sporadically but in rare cases can be associated with syndromes. These tumor entities show characteristic morphological changes,
Bremmer, Felix, Schweyer, Stefan
openaire   +2 more sources

Adult Type Granulosa Cell Tumor of the Testis

open access: yesKorean Journal of Urology, 2008
Dong Jun Kim, Dong Woo Song, Sang Yeop Yi, Woon Yong Yun, Tae Yung Jeong From the Departments of Urology and Pathology, College of Medicine, Kwandong University, Goyang, Korea Testicular granulosa cell tumor (GCT) is a rare neoplasm. We report here on an incidentally discovered testicular granulosa cell tumor in a 36-year-old man.
Dong Jun Kim   +4 more
openaire   +1 more source

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