Results 221 to 230 of about 110,453 (370)

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

Beyond diabetes and obesity: GLP‐1 receptor agonists in disrupting the vicious cycle of metabolic dysfunction and neuroinflammation

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 1622-1637, March 2026.
Abstract Neurodegenerative diseases, including debilitating conditions like Alzheimer's and Parkinson's, are characterized by progressive neuronal loss, a process fundamentally driven by persistent chronic neuroinflammation and central metabolic dysfunction.
Renata Spezani, Carlos A. Mandarim‐de‐Lacerda   +1 more
wiley   +1 more source

Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus [PDF]

, 2019
Yu Zheng, Lin Dong, Yanzi Zhong, Bin Luo, Shengsheng Liu, Erkang Fei, Xinsheng Lai, Suqi Zou, Shunqi Wang   +8 more
openalex   +1 more source

4R Tau Modulates Cocaine-Associated Memory through Adult Dorsal Hippocampal Neurogenesis [PDF]

, 2021
Hong‐Chun Li, Wei Xu, Denian Wang, Liang Wang, Qiyao Fang, Xuemei Wan, Jiamei Zhang, Yi-Ming Hu, Huifang Li, Jie Zhang, Zhen Yang, Chunqi Liu, Xiaocong Liu, Yonghai Wang, Bin Liu, Zhengtao Hu, Ying Zhao, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Cen   +21 more
openalex   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Regulation of adult hippocampal neurogenesis by microglia in the healthy and injured brain [PDF]

, 2023
Zhaolin Fu, RunZi YANG, Peng Hao
openalex   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

Exercise-Induced Increases of Corticosterone Contribute to Exercise-Enhanced Adult Hippocampal Neurogenesis in Mice

, 2021
Tzu-Feng Wang, Sheng‐Feng Tsai, Ziwei Zhao, Monica Meng‐Chun Shih, Chia‐Yih Wang, Tingting Yang, Yu‐Min Kuo   +6 more
openalex   +1 more source

Traumatic brain injury modifies adult hippocampal neural stem cell fate to promote neurogenesis at the cost of astrogliogenesis [PDF]

, 2023
Pascal Bielefeld, Araks Martirosyan, A. Apresyan, Gideon F. Meerhoff, Francisco Pestana, Suresh Poovathingal, N Reijners, Wim de Koning, RA Clement, I Van de Veen, E Toledo, Irene Durá, Svetlana Hovhannisyan, B. Nilges, A. Bogdoll, N. Kashikar, P. Lucassen, TG Belgard, JM Encinas, MG Holt, CP Fitzsimons   +20 more
openalex   +1 more source

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

Advanced Science, Volume 13, Issue 8, 9 February 2026.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen, Shuyang Yao, Sihui Cheng, Jiayi Tian, Ang Li, Yusen Yan, Xiang Zhang, Yuanjing Liu, Yumeng Wang, Qichen Cao, Chenglin Miao   +10 more
wiley   +1 more source