Neuron’s little helper: the role of primary cilia in neurogenesis [PDF]
, 2019 The generation of new neurons involves a great variety of cell-extrinsic and cell-intrinsic signals. The primary cilium, long regarded as an “evolutionary vestige,” has emerged as an essential signaling hub in many cells, including neural progenitors and
Badano, José L. +2 more
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Absent or low rate of adult neurogenesis in the hippocampus of bats (Chiroptera) [PDF]
, 2007 Bats are the only flying mammals and have well developed navigation abilities for 3D-space. Even bats with comparatively small home ranges cover much larger territories than rodents, and long-distance migration by some species is unique among small ...
Winter, Y +19 more
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Hippocampal neurogenesis and antidepressive therapy: shocking relations. [PDF]
, 2014 Speculations on the involvement of hippocampal neurogenesis, a form of neuronal plasticity, in the aetiology of depression and the mode of action of antidepressive therapies, started to arise more than a decade ago.
Aigner, Ludwig +15 more
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Neural stem cell biology and neurogenesis in mouse models of aging and Alzheimer's disease [PDF]
, 2006 The etiology of Alzheimer’s disease (AD) remains a great challenge for neurological research. Extensive investigations for almost one hundred years have led to profound insights of the pathological and molecular mechanisms that affect the AD brain, and
Ermini, Florian V.
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Morris Water Maze Learning in Two Rat Strains Increases the Expression of the Polysialylated Form of the Neural Cell Adhesion Molecule in the Dentate Gyrus But Has No Effect on Hippocampal Neurogenesis [PDF]
, 2005 In the current study, the authors investigated whether Morris water maze learning induces alterations in hippocampal neurogenesis or neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus.
Wallinga, Alinde E., +10 more
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Investigating the role of hippocampal neurogenesis in Alzheimer's disease. [PDF]
, 2022 openNeurogenesis is a form of plasticity that occurs constitutively in the neurogenic niches of the mammalian brain. Immature granule cells arising from adult hippocampal neurogenic niche, contribute to unique brain functions in rodents and recent ...
CIAGHI, SABINA
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Dual R-Smads interplay in the regulation of vertebrate neurogenesis [PDF]
, 2014 During neurogenesis, multiple regulatory networks integrate extracellular and intracellular signals to ensure proper final numbers for each neuronal subtype at the end of the developmental process.
Sanz, Adriana L., Miguez Gómez, David
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Performance on a pattern separation task by Alzheimer's patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E is an element of 4 status and cerebrospinal fluid amyloid-beta 42 levels [PDF]
, 2014 Introduction: Emerging evidence suggests that decreased adult hippocampal neurogenesis represents an early critical event in the course of Alzheimer's disease (AD).
Annas, Peter +14 more
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RNA-binding protein signaling in adult neurogenesis
, 2022 The process of neurogenesis in the brain, including cell proliferation, differentiation, survival, and maturation, results in the formation of new functional neurons.
Wui-Man, Lau Benson +5 more
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Chronic treatment with the GLP1 analogue liraglutide increases cell proliferation and differentiation into neurons in an AD mouse model [PDF]
, 2013 Neurogenesis is a life long process, but the rate of cell proliferation and differentiation decreases with age. In Alzheimer's patients, along with age, the presence of Aβ in the brain inhibits this process by reducing stem cell proliferation and cell ...
Vadivel Parthsarathy +7 more
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