Hippocampal neurogenesis and antidepressive therapy: shocking relations. [PDF]
Speculations on the involvement of hippocampal neurogenesis, a form of neuronal plasticity, in the aetiology of depression and the mode of action of antidepressive therapies, started to arise more than a decade ago.
Aigner, Ludwig +15 more
core +1 more source
Absent or low rate of adult neurogenesis in the hippocampus of bats (Chiroptera) [PDF]
Bats are the only flying mammals and have well developed navigation abilities for 3D-space. Even bats with comparatively small home ranges cover much larger territories than rodents, and long-distance migration by some species is unique among small ...
Winter, Y +19 more
core +2 more sources
Experiments on fruit flies are shedding new light on the evolution and development of the nervous system in metamorphosing insects.
openaire +3 more sources
Neural stem cell biology and neurogenesis in mouse models of aging and Alzheimer's disease [PDF]
The etiology of Alzheimer’s disease (AD) remains a great challenge for neurological research. Extensive investigations for almost one hundred years have led to profound insights of the pathological and molecular mechanisms that affect the AD brain, and
Ermini, Florian V.
core +1 more source
Morris Water Maze Learning in Two Rat Strains Increases the Expression of the Polysialylated Form of the Neural Cell Adhesion Molecule in the Dentate Gyrus But Has No Effect on Hippocampal Neurogenesis [PDF]
In the current study, the authors investigated whether Morris water maze learning induces alterations in hippocampal neurogenesis or neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus.
Wallinga, Alinde E., +10 more
core +1 more source
Investigating the role of hippocampal neurogenesis in Alzheimer's disease. [PDF]
openNeurogenesis is a form of plasticity that occurs constitutively in the neurogenic niches of the mammalian brain. Immature granule cells arising from adult hippocampal neurogenic niche, contribute to unique brain functions in rodents and recent ...
CIAGHI, SABINA
core
Ultrasound-Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis-Macrophage Crosstalk in Diabetic Wound Healing. [PDF]
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Wang K +13 more
europepmc +2 more sources
Dual R-Smads interplay in the regulation of vertebrate neurogenesis [PDF]
During neurogenesis, multiple regulatory networks integrate extracellular and intracellular signals to ensure proper final numbers for each neuronal subtype at the end of the developmental process.
Sanz, Adriana L., Miguez Gómez, David
core +1 more source
Ependymal cilia beating induces an actin network to protect centrioles against shear stress
Ependymal ciliary beating contributes to the flow of cerebrospinal fluid in the brain ventricles and these cilia resist the flow forces. Here the authors show that the assembly of a dense actin network around the centrioles is induced by cilia beating to
Alexia Mahuzier +12 more
doaj +1 more source
Summary: Stem cell-derived neurons are generally obtained in mass cultures that lack both spatial organization and any meaningful connectivity. We implement a microfluidic system for long-term culture of human neurons with patterned projections and ...
Angelo Iannielli +9 more
doaj +1 more source

