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Adult Neurogenesis in Drosophila [PDF]

open access: yesCell Reports, 2013
Adult neurogenesis has been linked to several cognitive functions and neurological disorders. Description of adult neurogenesis in a model organism like Drosophila could facilitate the genetic study of normal and abnormal neurogenesis in the adult brain.
Ismael Fernández-Hernández   +2 more
doaj   +7 more sources

Testosterone and Adult Neurogenesis [PDF]

open access: yesBiomolecules, 2020
It is now well established that neurogenesis occurs throughout adulthood in select brain regions, but the functional significance of adult neurogenesis remains unclear. There is considerable evidence that steroid hormones modulate various stages of adult
Mark D. Spritzer, Ethan A. Roy
doaj   +3 more sources

Adult-neurogenesis allows for representational stability and flexibility in early olfactory system [PDF]

open access: yeseLife
In the olfactory system, adult-neurogenesis results in the continuous reorganization of synaptic connections and network architecture throughout the animal’s life.
Zhen Chen, Krishnan Padmanabhan
doaj   +2 more sources

Multimodal insights into adult neurogenesis: An integrative review of multi-omics approaches [PDF]

open access: yesHeliyon
Adult neural stem cells divide to produce neurons that migrate to preexisting neuronal circuits in a process named adult neurogenesis. Adult neurogenesis is one of the most exciting areas of current neuroscience, and it may be involved in a range of ...
Jin Li   +8 more
doaj   +2 more sources

Neurogenesis in the embryonic and adult brain: same regulators, different roles.

open access: yesFrontiers in Cellular Neuroscience, 2014
Neurogenesis persists in adult mammals in specific brain areas, known as neurogenic niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological stimuli and pathological states.
Noelia eUrban, François eGuillemot
doaj   +3 more sources

Inhibition of TGF-β signaling in microglia stimulates hippocampal adult neurogenesis and reduces anxiety-like behavior in adult mice [PDF]

open access: yesNature Communications
Adult neurogenesis in the subgranular zone (SGZ) has been implicated in cognitive and affective functions. The role of neuroinflammation and reactive microglia in SGZ neurogenesis is not well understood.
Kierra Ware   +12 more
doaj   +2 more sources

Adult neurogenesis: a real hope or a delusion? [PDF]

open access: yesNeural Regen Res
Adult neurogenesis, the process of creating new neurons, involves the coordinated division, migration, and differentiation of neural stem cells. This process is restricted to neurogenic niches located in two distinct areas of the brain: the subgranular zone of the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricle ...
Hussain G   +7 more
europepmc   +3 more sources

The intricate interplay between microglia and adult neurogenesis in Alzheimer’s disease [PDF]

open access: yesFrontiers in Cellular Neuroscience
Microglia, the resident immune cells of the central nervous system, play a crucial role in regulating adult neurogenesis and contribute significantly to the pathogenesis of Alzheimer’s disease (AD).
Iris Früholz   +4 more
doaj   +2 more sources

What can traditional Chinese medicine do for adult neurogenesis?

open access: yesFrontiers in Neuroscience, 2023
Adult neurogenesis plays a crucial role in cognitive function and mood regulation, while aberrant adult neurogenesis contributes to various neurological and psychiatric diseases.
Wei Shen   +7 more
doaj   +1 more source

Epilepsy and Adult Neurogenesis [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2015
Seizure activity in the hippocampal region strongly affects stem cell-associated plasticity in the adult dentate gyrus. Here, we describe how seizures in rodent models of mesial temporal lobe epilepsy (mTLE) affect multiple steps in the developmental course from the dividing neural stem cell to the migrating and integrating newborn neuron. Furthermore,
Jessberger, Sebastian, Parent, Jack M
openaire   +3 more sources

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