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Adult Neurogenesis in Drosophila [PDF]
Adult neurogenesis has been linked to several cognitive functions and neurological disorders. Description of adult neurogenesis in a model organism like Drosophila could facilitate the genetic study of normal and abnormal neurogenesis in the adult brain.
Ismael Fernández-Hernández +2 more
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Testosterone and Adult Neurogenesis [PDF]
It is now well established that neurogenesis occurs throughout adulthood in select brain regions, but the functional significance of adult neurogenesis remains unclear. There is considerable evidence that steroid hormones modulate various stages of adult
Mark D. Spritzer, Ethan A. Roy
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Neurogenesis in the embryonic and adult brain: same regulators, different roles.
Neurogenesis persists in adult mammals in specific brain areas, known as neurogenic niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological stimuli and pathological states.
Noelia eUrban, François eGuillemot
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What can traditional Chinese medicine do for adult neurogenesis?
Adult neurogenesis plays a crucial role in cognitive function and mood regulation, while aberrant adult neurogenesis contributes to various neurological and psychiatric diseases.
Wei Shen +7 more
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Epilepsy and Adult Neurogenesis [PDF]
Seizure activity in the hippocampal region strongly affects stem cell-associated plasticity in the adult dentate gyrus. Here, we describe how seizures in rodent models of mesial temporal lobe epilepsy (mTLE) affect multiple steps in the developmental course from the dividing neural stem cell to the migrating and integrating newborn neuron. Furthermore,
Jessberger, Sebastian, Parent, Jack M
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Alzheimer’s disease (AD) is a neurodegenerative disease that is characterized by irreversible cognitive declines. Senile plaques formed by amyloid-β (Aβ) peptides and neurofibrillary tangles, consisting of hyperphosphorylated tau protein accumulation ...
Hyeon Soo Kim +7 more
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Adult Neurogenesis in Fish [PDF]
Teleost fish have a remarkable neurogenic and regenerative capacity in the adult throughout the rostrocaudal axis of the brain. The distribution of proliferation zones shows a remarkable conservation, even in distantly related teleost species, suggesting a common teleost ground plan of proliferation zones.
Julia, Ganz, Michael, Brand
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Adult Neurogenesis in Humans [PDF]
Adult neurogenesis appears very well conserved among mammals. It was, however, not until recently that quantitative data on the extent of this process became available in humans, largely because of methodological challenges to study this process in man.
Olaf Bergmann +2 more
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Signaling in adult neurogenesis [PDF]
Neural stem cells (NSCs) in the adult brain continuously supply new neurons to the hippocampal dentate gyrus (DG) and the olfactory bulb (OB). Recent studies indicate that the progression from neural precursor cells (NPCs) to mature neurons is tightly controlled by coordinate cell-intrinsic programs and external signals within the neurogenic niche.
Yangling, Mu, Star W, Lee, Fred H, Gage
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Dopamine and adult neurogenesis [PDF]
AbstractDopamine is an important neurotransmitter implicated in the regulation of mood, motivation and movement. We have reviewed here recent data suggesting that dopamine, in addition to being a neurotransmitter, also plays a role in the regulation of endogenous neurogenesis in the adult mammalian brain. In addition, we approach a highly controversial
Andreas, Borta, Günter U, Höglinger
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