Adult Neurogenesis in Drosophila [PDF]
Adult neurogenesis has been linked to several cognitive functions and neurological disorders. Description of adult neurogenesis in a model organism like Drosophila could facilitate the genetic study of normal and abnormal neurogenesis in the adult brain.
Ismael Fernández-Hernández +2 more
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Testosterone and Adult Neurogenesis [PDF]
It is now well established that neurogenesis occurs throughout adulthood in select brain regions, but the functional significance of adult neurogenesis remains unclear. There is considerable evidence that steroid hormones modulate various stages of adult
Mark D. Spritzer, Ethan A. Roy
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Adult-neurogenesis allows for representational stability and flexibility in early olfactory system [PDF]
In the olfactory system, adult-neurogenesis results in the continuous reorganization of synaptic connections and network architecture throughout the animal’s life.
Zhen Chen, Krishnan Padmanabhan
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Multimodal insights into adult neurogenesis: An integrative review of multi-omics approaches [PDF]
Adult neural stem cells divide to produce neurons that migrate to preexisting neuronal circuits in a process named adult neurogenesis. Adult neurogenesis is one of the most exciting areas of current neuroscience, and it may be involved in a range of ...
Jin Li +8 more
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Neurogenesis in the embryonic and adult brain: same regulators, different roles.
Neurogenesis persists in adult mammals in specific brain areas, known as neurogenic niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological stimuli and pathological states.
Noelia eUrban, François eGuillemot
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Inhibition of TGF-β signaling in microglia stimulates hippocampal adult neurogenesis and reduces anxiety-like behavior in adult mice [PDF]
Adult neurogenesis in the subgranular zone (SGZ) has been implicated in cognitive and affective functions. The role of neuroinflammation and reactive microglia in SGZ neurogenesis is not well understood.
Kierra Ware +12 more
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Adult neurogenesis: a real hope or a delusion? [PDF]
Adult neurogenesis, the process of creating new neurons, involves the coordinated division, migration, and differentiation of neural stem cells. This process is restricted to neurogenic niches located in two distinct areas of the brain: the subgranular zone of the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricle ...
Hussain G +7 more
europepmc +3 more sources
The intricate interplay between microglia and adult neurogenesis in Alzheimer’s disease [PDF]
Microglia, the resident immune cells of the central nervous system, play a crucial role in regulating adult neurogenesis and contribute significantly to the pathogenesis of Alzheimer’s disease (AD).
Iris Früholz +4 more
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What can traditional Chinese medicine do for adult neurogenesis?
Adult neurogenesis plays a crucial role in cognitive function and mood regulation, while aberrant adult neurogenesis contributes to various neurological and psychiatric diseases.
Wei Shen +7 more
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Epilepsy and Adult Neurogenesis [PDF]
Seizure activity in the hippocampal region strongly affects stem cell-associated plasticity in the adult dentate gyrus. Here, we describe how seizures in rodent models of mesial temporal lobe epilepsy (mTLE) affect multiple steps in the developmental course from the dividing neural stem cell to the migrating and integrating newborn neuron. Furthermore,
Jessberger, Sebastian, Parent, Jack M
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