Results 11 to 20 of about 83,360 (210)

HDAC1 Regulates Neuronal Differentiation

Frontiers in Molecular Neuroscience, 2022
In adult hippocampal neurogenesis, chromatin modification plays an important role in neural stem cell self-renewal and differentiation by regulating the expression of multiple genes. Histone deacetylases (HDACs), which remove acetyl groups from histones,
Vanesa Nieto-Estevez, Vanesa Nieto-Estevez, Gopakumar Changarathil, Gopakumar Changarathil, Adebayo Olukayode Adeyeye, Adebayo Olukayode Adeyeye, Marissa Olga Coppin, Marissa Olga Coppin, Rawan Serena Kassim, Rawan Serena Kassim, Jingfei Zhu, Jenny Hsieh, Jenny Hsieh   +12 more
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Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein

Stem Cell Reports, 2016
Adult hippocampal neurogenesis was impaired in several Alzheimer's disease models overexpressing mutant human amyloid precursor protein (hAPP). However, the effects of wild-type hAPP on adult neurogenesis and whether the impaired adult hippocampal ...
Hongyu Pan, Dongpi Wang, Xiaoqin Zhang, Dongming Zhou, Heng Zhang, Qi Qian, Xiao He, Zhaoling Liu, Yunjin Liu, Tingting Zheng, Ling Zhang, Mingkai Wang, Binggui Sun   +12 more
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L-Lactate Promotes Adult Hippocampal Neurogenesis

Frontiers in Neuroscience, 2019
Neurogenesis, the formation of new neurons in the adult brain, is important for memory formation and extinction. One of the most studied external interventions that affect the rate of adult neurogenesis is physical exercise.
Yaeli Lev-Vachnish, Yaeli Lev-Vachnish, Yaeli Lev-Vachnish, Sharon Cadury, Sharon Cadury, Sharon Cadury, Aviva Rotter-Maskowitz, Aviva Rotter-Maskowitz, Aviva Rotter-Maskowitz, Noa Feldman, Noa Feldman, Noa Feldman, Asael Roichman, Tomer Illouz, Tomer Illouz, Alexander Varvak, Raneen Nicola, Raneen Nicola, Ravit Madar, Ravit Madar, Ravit Madar, Eitan Okun, Eitan Okun, Eitan Okun   +23 more
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Brain Infection by Group B Streptococcus Induces Inflammation and Affects Neurogenesis in the Adult Mouse Hippocampus

Cells, 2023
Central nervous system infections caused by pathogens crossing the blood–brain barrier are extremely damaging and trigger cellular alterations and neuroinflammation.
Katerina Segklia, Rebecca Matsas, Florentia Papastefanaki   +2 more
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Adult Neurogenesis in Drosophila

Cell Reports, 2013
Adult neurogenesis has been linked to several cognitive functions and neurological disorders. Description of adult neurogenesis in a model organism like Drosophila could facilitate the genetic study of normal and abnormal neurogenesis in the adult brain.
Ismael Fernández-Hernández, Christa Rhiner, Eduardo Moreno   +2 more
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Targeted deletion of the ERK5 MAP kinase impairs neuronal differentiation, migration, and survival during adult neurogenesis in the olfactory bulb. [PDF]

PLoS ONE, 2013
Recent studies have led to the exciting idea that adult-born neurons in the olfactory bulb (OB) may be critical for complex forms of olfactory behavior in mice. However, signaling mechanisms regulating adult OB neurogenesis are not well defined.
Tan Li, Yung-Wei Pan, Wenbin Wang, Glen Abel, Junhui Zou, Lihong Xu, Daniel R Storm, Zhengui Xia   +7 more
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Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis

Cell Reports, 2019
Summary: Although adult neurogenesis recapitulates processes that occur during embryonic development, it exhibits distinct characteristics from the embryonic counterpart.
Yuhan Wang, Ye Guo, Changyong Tang, Xiu Han, Mingyue Xu, Jing Sun, Yifei Zhao, Yiwen Zhang, Min Wang, Xiaofeng Cao, Xiaojuan Zhu, Weixiang Guo   +11 more
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THE SOCIAL ENVIRONMENT AND NEUROGENESIS IN THE ADULT MAMMALIAN BRAIN

Frontiers in Human Neuroscience, 2012
Adult neurogenesis—the formation of new neurons in adulthood—has been shown to be modulated by a variety of endogenous (e.g., trophic factors, neurotransmitters, and hormones) as well as exogenous (e.g., physical activity and environmental complexity ...
Claudia eLieberwirth, Zuoxin eWang
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Doxycycline increases neurogenesis and reduces microglia in the adult hippocampus.

Frontiers in Neuroscience, 2013
Adult hippocampal neurogenesis results in the continuous formation of new neurons and is a process of brain plasticity involved in learning and memory. Although inducible-reversible transgenic mouse models are increasingly being used to investigate adult
Sebastien eSultan, Elias eGebara, Nicolas eToni   +2 more
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Role of adult hippocampal neurogenesis in stress resilience

Neurobiology of Stress, 2015
There is a growing appreciation that adult hippocampal neurogenesis plays a role in emotional and cognitive processes related to psychiatric disorders. Although many studies have investigated the effects of stress on adult hippocampal neurogenesis, most ...
Brunno R. Levone, John F. Cryan, Olivia F. O'Leary   +2 more
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