Results 11 to 20 of about 152,418 (295)

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. [PDF]

Nature, 2018
New neurons continue to be generated in the subgranular zone of the dentate gyrus of the adult mammalian hippocampus. This process has been linked to learning and memory, stress and exercise, and is thought to be altered in neurological disease.
A Fahrner, AD Workman, Antonio J. Gutierrez, Arantxa Cebrian-Silla, Arnold R. Kriegstein, Arturo Alvarez-Buylla, AS Hill, B Seri, B Steiner, C Wang, CV Dennis, Dashi Qi, David James, DR Kornack, DR Kornack, E Gould, E Gould, Edward F. Chang, Eric J. Huang, G Kempermann, Gary W. Mathern, GW Mathern, H Suh, H van Praag, H van Praag, HJ Kang, J Altman, J Altman, JE Malberg, JJ Breunig, Jose Manuel Garcia-Verdugo, Julia Chang, Kadellyn Sandoval, Kevin W. Kelley, KJ Mathews, KL Spalding, Kurtis I. Auguste, M Komitova, M Venere, Mercedes F. Paredes, MF Eckenhoff, Michael C. Oldham, N Patzke, N Sanai, P Yang, PS Eriksson, R Knoth, S Lugert, Shawn F. Sorrells, Simone Mayer, T Sugiyama, TE Bakken, Y Zhang, Zhengang Yang   +53 more
core   +3 more sources

What can traditional Chinese medicine do for adult neurogenesis?

Frontiers in Neuroscience, 2023
Adult neurogenesis plays a crucial role in cognitive function and mood regulation, while aberrant adult neurogenesis contributes to various neurological and psychiatric diseases.
Wei Shen, Wei Shen, Wei Shen, Ning Jiang, Ning Jiang, Wenxia Zhou, Wenxia Zhou, Wenxia Zhou   +7 more
doaj   +1 more source

Epilepsy and Adult Neurogenesis [PDF]

Cold Spring Harbor Perspectives in Biology, 2015
Seizure activity in the hippocampal region strongly affects stem cell-associated plasticity in the adult dentate gyrus. Here, we describe how seizures in rodent models of mesial temporal lobe epilepsy (mTLE) affect multiple steps in the developmental course from the dividing neural stem cell to the migrating and integrating newborn neuron. Furthermore,
Jessberger, Sebastian, Parent, Jack M
openaire   +2 more sources

Adult Neurogenesis Workshop report [PDF]

Frontiers in Neuroscience, 2010
The workshop was held on July 3, 2009, at the University of Toronto, Canada, and provided a forum for researchers in the field of adult neurogenesis to learn about recent progress in the field, and to present and discuss their ongoing research. The program included talks by mostly local trainees and faculty from the field of adult neurogenesis, who ...
Rosenzweig, Shira, Luu, Paul
openaire   +3 more sources

Relationship between adult subventricular neurogenesis and Alzheimer’s disease: Pathologic roles and therapeutic implications

Frontiers in Aging Neuroscience, 2022
Alzheimer’s disease (AD) is a neurodegenerative disease that is characterized by irreversible cognitive declines. Senile plaques formed by amyloid-β (Aβ) peptides and neurofibrillary tangles, consisting of hyperphosphorylated tau protein accumulation ...
Hyeon Soo Kim, Seong Min Shin, Sujin Kim, Sujin Kim, Yunkwon Nam, Anji Yoo, Minho Moon, Minho Moon   +7 more
doaj   +1 more source

Detrimental role of prolonged sleep deprivation on adult neurogenesis [PDF]

, 2015
Adult mammalian brains continuously generate new neurons, a phenomenon called adult neurogenesis. Both environmental stimuli and endogenous factors are important regulators of adult neurogenesis. Sleep has an important role in normal brain physiology and
Arias-Carrión, Oscar, Fernandes, Carina, García-García, Fabio, Herrera-Solís, Andrea, Machado, Sergio, Murillo-Rodríguez, Eric, Rocha, Nuno, Rocha, Susana, Salas-Pacheco, José, Yuan, Ti-Fei   +9 more
core   +6 more sources

Prenatal stress inhibits hippocampal neurogenesis but spares olfactory bulb neurogenesis. [PDF]

PLoS ONE, 2013
The dentate gyrus (DG) and the olfactory bulb (OB) are two regions of the adult brain in which new neurons are integrated daily in the existing networks.
Laure Belnoue, Noelle Grosjean, Elodie Ladevèze, Djoher Nora Abrous, Muriel Koehl   +4 more
doaj   +1 more source

HDAC1 Regulates Neuronal Differentiation

Frontiers in Molecular Neuroscience, 2022
In adult hippocampal neurogenesis, chromatin modification plays an important role in neural stem cell self-renewal and differentiation by regulating the expression of multiple genes. Histone deacetylases (HDACs), which remove acetyl groups from histones,
Vanesa Nieto-Estevez, Vanesa Nieto-Estevez, Gopakumar Changarathil, Gopakumar Changarathil, Adebayo Olukayode Adeyeye, Adebayo Olukayode Adeyeye, Marissa Olga Coppin, Marissa Olga Coppin, Rawan Serena Kassim, Rawan Serena Kassim, Jingfei Zhu, Jenny Hsieh, Jenny Hsieh   +12 more
doaj   +1 more source

Brain Infection by Group B Streptococcus Induces Inflammation and Affects Neurogenesis in the Adult Mouse Hippocampus

Cells, 2023
Central nervous system infections caused by pathogens crossing the blood–brain barrier are extremely damaging and trigger cellular alterations and neuroinflammation.
Katerina Segklia, Rebecca Matsas, Florentia Papastefanaki   +2 more
doaj   +1 more source

Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein

Stem Cell Reports, 2016
Adult hippocampal neurogenesis was impaired in several Alzheimer's disease models overexpressing mutant human amyloid precursor protein (hAPP). However, the effects of wild-type hAPP on adult neurogenesis and whether the impaired adult hippocampal ...
Hongyu Pan, Dongpi Wang, Xiaoqin Zhang, Dongming Zhou, Heng Zhang, Qi Qian, Xiao He, Zhaoling Liu, Yunjin Liu, Tingting Zheng, Ling Zhang, Mingkai Wang, Binggui Sun   +12 more
doaj   +1 more source