Results 21 to 30 of about 1,664,491 (187)

Prenatal stress inhibits hippocampal neurogenesis but spares olfactory bulb neurogenesis. [PDF]

PLoS ONE, 2013
The dentate gyrus (DG) and the olfactory bulb (OB) are two regions of the adult brain in which new neurons are integrated daily in the existing networks.
Laure Belnoue, Noelle Grosjean, Elodie Ladevèze, Djoher Nora Abrous, Muriel Koehl   +4 more
doaj   +1 more source

Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein

Stem Cell Reports, 2016
Adult hippocampal neurogenesis was impaired in several Alzheimer's disease models overexpressing mutant human amyloid precursor protein (hAPP). However, the effects of wild-type hAPP on adult neurogenesis and whether the impaired adult hippocampal ...
Hongyu Pan, Dongpi Wang, Xiaoqin Zhang, Dongming Zhou, Heng Zhang, Qi Qian, Xiao He, Zhaoling Liu, Yunjin Liu, Tingting Zheng, Ling Zhang, Mingkai Wang, Binggui Sun   +12 more
doaj   +1 more source

HDAC1 Regulates Neuronal Differentiation

Frontiers in Molecular Neuroscience, 2022
In adult hippocampal neurogenesis, chromatin modification plays an important role in neural stem cell self-renewal and differentiation by regulating the expression of multiple genes. Histone deacetylases (HDACs), which remove acetyl groups from histones,
Vanesa Nieto-Estevez, Vanesa Nieto-Estevez, Gopakumar Changarathil, Gopakumar Changarathil, Adebayo Olukayode Adeyeye, Adebayo Olukayode Adeyeye, Marissa Olga Coppin, Marissa Olga Coppin, Rawan Serena Kassim, Rawan Serena Kassim, Jingfei Zhu, Jenny Hsieh, Jenny Hsieh   +12 more
doaj   +1 more source

Hippocampal neurogenesis and antidepressive therapy: shocking relations. [PDF]

, 2014
Speculations on the involvement of hippocampal neurogenesis, a form of neuronal plasticity, in the aetiology of depression and the mode of action of antidepressive therapies, started to arise more than a decade ago.
Aigner, Ludwig, Ludwig Aigner, Lange, Simona, Marschallinger, Julia, O’Sullivan, Anna, Zaunmair, Pia, Couillard-Despres, Sebastien, Simona Lange, Sebastien Couillard-Despres, Christian Geretsegger, Anna O’Sullivan, Pia Zaunmair, Peter Rotheneichner, Rotheneichner, Peter, Geretsegger, Christian, Julia Marschallinger   +15 more
core   +1 more source

Brain Infection by Group B Streptococcus Induces Inflammation and Affects Neurogenesis in the Adult Mouse Hippocampus

Cells, 2023
Central nervous system infections caused by pathogens crossing the blood–brain barrier are extremely damaging and trigger cellular alterations and neuroinflammation.
Katerina Segklia, Rebecca Matsas, Florentia Papastefanaki   +2 more
doaj   +1 more source

Targeted deletion of the ERK5 MAP kinase impairs neuronal differentiation, migration, and survival during adult neurogenesis in the olfactory bulb. [PDF]

PLoS ONE, 2013
Recent studies have led to the exciting idea that adult-born neurons in the olfactory bulb (OB) may be critical for complex forms of olfactory behavior in mice. However, signaling mechanisms regulating adult OB neurogenesis are not well defined.
Tan Li, Yung-Wei Pan, Wenbin Wang, Glen Abel, Junhui Zou, Lihong Xu, Daniel R Storm, Zhengui Xia   +7 more
doaj   +1 more source

Neurogenesis in the Adult Hippocampus [PDF]

Cold Spring Harbor Perspectives in Biology, 2015
Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the most attention, because it is involved in higher cognitive function, most notably memory processes, and certain affective behaviors. Adult hippocampal neurogenesis is also found in humans at a considerable level and appears to contribute significantly to hippocampal
Kempermann, Gerd, Song, Hongjun, Gage, Fred H   +2 more
openaire   +3 more sources

Propofol Anesthesia Impairs the Maturation and Survival of Adult-born Hippocampal Neurons [PDF]

, 2013
BACKGROUND:: Adult neurogenesis occurs in the hippocampus of most mammals, including humans, and plays an important role in hippocampal-dependent learning. This process is highly regulated by neuronal activity and might therefore be vulnerable to
Krzisch, M., Demeter, K., Toni, Nicolas, Sultan, S., Sandell, J., Vutskits, László, Demeter, Kornél, Sultan, Sébastien, Toni, N., Krzisch, Marine, Sandell, Julie, Vutskits, L., Toni N, Demeter K, Krzisch M, Vutskits L, Sultan S, Sandell J   +17 more
core   +1 more source

Neurogenesis in the Adult Goldfish Cerebellum [PDF]

The Anatomical Record, 2010
AbstractNeurogenesis was studied in the cerebellum of adult goldfish, to establish the phenomenon in this popular laboratory animal model. BrdU and proliferating cell nuclear antigen labeling revealed a high rate of cell proliferation within the molecular layer of the cerebellar corpus and valve.
Delgado, Luz M., Schmachtenberg, Oliver
openaire   +4 more sources

Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis

Cell Reports, 2019
Summary: Although adult neurogenesis recapitulates processes that occur during embryonic development, it exhibits distinct characteristics from the embryonic counterpart.
Yuhan Wang, Ye Guo, Changyong Tang, Xiu Han, Mingyue Xu, Jing Sun, Yifei Zhao, Yiwen Zhang, Min Wang, Xiaofeng Cao, Xiaojuan Zhu, Weixiang Guo   +11 more
doaj   +1 more source