Results 21 to 30 of about 83,360 (210)

Absent or low rate of adult neurogenesis in the hippocampus of bats (Chiroptera). [PDF]

PLoS ONE, 2007
Bats are the only flying mammals and have well developed navigation abilities for 3D-space. Even bats with comparatively small home ranges cover much larger territories than rodents, and long-distance migration by some species is unique among small ...
Irmgard Amrein, Dina K N Dechmann, York Winter, Hans-Peter Lipp   +3 more
doaj   +1 more source

Genetic Methods to Identify and Manipulate Newly born Neurons in the Adult Brain

Frontiers in Neuroscience, 2011
Although mammalian neurogenesis is mostly completed by the perinatal period, new neurons are continuously generated in the subventricular zone of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus.
Itaru eImayoshi, Masayuki eSakamoto, Ryoichiro eKageyama   +2 more
doaj   +1 more source

What do we know about adult mammalian hippocampal neurogenesis so far? [PDF]

Medicinski Podmladak
It is known that the adult mammalian brain can add new neurons throughout the whole lifespan. Neural stem cells reside in the subgranular zone of the dentate gyrus of the hippocampus and the subventricular zone of the rostral lateral ventricle.
Jeremić Rada, Brkić Predrag, Dacić Sanja   +2 more
doaj   +1 more source

Adiponectin Mediates Running-Restored Hippocampal Neurogenesis in Streptozotocin-Induced Type 1 Diabetes in Mice

Frontiers in Neuroscience, 2018
Streptozotocin (STZ)-induced diabetes impairs learning and memory performance and reduces adult hippocampal neurogenesis. Physical exercise brings beneficial effects.
Suk-Yu Yau, Thomas Ho-Yin Lee, Ang Li, Aimin Xu, Aimin Xu, Aimin Xu, Kwok-Fai So, Kwok-Fai So, Kwok-Fai So   +8 more
doaj   +1 more source

Strength exercise weakens aerobic exercise-induced cognitive improvements in rats. [PDF]

PLoS ONE, 2018
Aerobic exercise improves cognitive function and adult hippocampal neurogenesis. However, the effects of aerobic exercise combined with strength exercise on cognitive function and adult hippocampal neurogenesis are still unknown.
Yongsheng Lan, Zhaoyuan Huang, Yanjie Jiang, Xuehua Zhou, Jingyu Zhang, Dianyu Zhang, Bo Wang, Guangqing Hou   +7 more
doaj   +1 more source

Regulator of G protein signaling 6 mediates exercise-induced recovery of hippocampal neurogenesis, learning, and memory in a mouse model of Alzheimer’s disease

Neural Regeneration Research
Hippocampal neuronal loss causes cognitive dysfunction in Alzheimer’s disease. Adult hippocampal neurogenesis is reduced in patients with Alzheimer’s disease.
Mackenzie M. Spicer, Jianqi Yang, Daniel Fu, Alison N. DeVore, Marisol Lauffer, Nilufer S. Atasoy, Deniz Atasoy, Rory A. Fisher   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Current understanding and prospects for targeting neurogenesis in the treatment of cognitive impairment

Neural Regeneration Research
Adult hippocampal neurogenesis is linked to memory formation in the adult brain, with new neurons in the hippocampus exhibiting greater plasticity during their immature stages compared to mature neurons. Abnormal adult hippocampal neurogenesis is closely
Ye Liu, Xibing Ding, Shushan Jia, Xiyao Gu   +3 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source