Results 1 to 10 of about 56,428 (116)

Roles of microglia in adult hippocampal neurogenesis in depression and their therapeutics

Frontiers in Immunology, 2023
Adult hippocampal neurogenesis generates functional neurons from neural progenitor cells in the hippocampal dentate gyrus (DG) to complement and repair neurons and neural circuits, thus benefiting the treatment of depression.
Jianbei Chen, Wenzhi Hao, Xiaowei Mo
exaly   +3 more sources

Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage

Neurobiology of Disease, 2008
It has not been reported whether thiamine deficiency (TD) affects hippocampal neurogenesis or not. Here, we explored the influence of TD at early pre-pathological lesion stage on hippocampal neurogenesis and the correlation between affected hippocampal ...
Na Zhao, Chunjiu Zhong, Neng Gong
exaly   +3 more sources

Adiponectin Mediates Running-Restored Hippocampal Neurogenesis in Streptozotocin-Induced Type 1 Diabetes in Mice

Frontiers in Neuroscience, 2018
Streptozotocin (STZ)-induced diabetes impairs learning and memory performance and reduces adult hippocampal neurogenesis. Physical exercise brings beneficial effects.
Suk-Yu Yau, Thomas H Lee, Aimin Xu
exaly   +3 more sources

Decreased hippocampal neurogenesis and post-stroke depression [PDF]

Frontiers in Psychiatry
Post-stroke depression (PSD) is a common and serious complication following stroke, affecting approximately one-third of survivors and contributing to poor functional recovery.
Xiangyue Tang, Lusen Ran, Wenfei Li
doaj   +2 more sources

What Is the Relationship Between Hippocampal Neurogenesis Across Different Stages of the Lifespan?

Frontiers in Neuroscience, 2022
Hippocampal neurogenesis has typically been studied during embryonic development or in adulthood, promoting the perception of two distinct phenomena.
Allison M. Bond, Guo-li Ming, Guo-li Ming, Guo-li Ming, Guo-li Ming, Hongjun Song, Hongjun Song, Hongjun Song, Hongjun Song   +8 more
doaj   +1 more source

IL-1β and HMGB1 are anti-neurogenic to endogenous neural stem cells in the sclerotic epileptic human hippocampus

Journal of Neuroinflammation, 2021
Background The dentate gyrus exhibits life-long neurogenesis of granule-cell neurons, supporting hippocampal dependent learning and memory. Both temporal lobe epilepsy patients and animal models frequently have hippocampal-dependent learning and memory ...
Malik Zaben, Niels Haan, Feras Sharouf, Aminul Ahmed, Lars E. Sundstrom, William P. Gray   +5 more
doaj   +1 more source

Does Impairment of Adult Neurogenesis Contribute to Pathophysiology of Alzheimer's Disease? A Still Open Question

Frontiers in Molecular Neuroscience, 2021
Adult hippocampal neurogenesis is a physiological mechanism contributing to hippocampal memory formation. Several studies associated altered hippocampal neurogenesis with aging and Alzheimer's disease (AD).
Domenica Donatella Li Puma, Domenica Donatella Li Puma, Roberto Piacentini, Roberto Piacentini, Claudio Grassi, Claudio Grassi   +5 more
doaj   +1 more source

Cholinergic and Neuroimmune Signaling Interact to Impact Adult Hippocampal Neurogenesis and Alcohol Pathology Across Development

Frontiers in Pharmacology, 2022
Alcohol (ethanol) use and misuse is a costly societal issue that can affect an individual across the lifespan. Alcohol use and misuse typically initiates during adolescence and generally continues into adulthood.
Victoria A. Macht, Ryan P. Vetreno, Ryan P. Vetreno, Fulton T. Crews, Fulton T. Crews, Fulton T. Crews   +5 more
doaj   +1 more source

Decreasing auditory input induces neurogenesis impairment in the hippocampus

Scientific Reports, 2021
Hearing loss is associated with cognitive decline and dementia risk. Sensorineural hearing loss suppresses hippocampal neurogenesis, resulting in cognitive decline.
Takaomi Kurioka, Sachiyo Mogi, Taku Yamashita   +2 more
doaj   +1 more source

Strength exercise weakens aerobic exercise-induced cognitive improvements in rats. [PDF]

PLoS ONE, 2018
Aerobic exercise improves cognitive function and adult hippocampal neurogenesis. However, the effects of aerobic exercise combined with strength exercise on cognitive function and adult hippocampal neurogenesis are still unknown.
Yongsheng Lan, Zhaoyuan Huang, Yanjie Jiang, Xuehua Zhou, Jingyu Zhang, Dianyu Zhang, Bo Wang, Guangqing Hou   +7 more
doaj   +1 more source