Results 11 to 20 of about 56,531 (215)
Evidences for Adult Hippocampal Neurogenesis in Humans [PDF]
The Journal of Neuroscience, 2021 The rodent hippocampus generates new neurons throughout life. This process, named adult hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the brains of numerous mammalian species. Direct evidence of adult neurogenesis in humans has remained elusive, although the occurrence of this phenomenon in the human dentate ...
Elena P. Moreno-Jiménez +4 more
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Hippocampal neurogenesis: Learning to remember [PDF]
Progress in Neurobiology, 2016 Alzheimer's disease, the most prevalent form of dementia in the elderly, is characterized by progressive memory loss and cognitive dysfunction. It has become increasingly clear that while neuronal cell loss in the entorhinal cortex and hippocampus occurs in Alzheimer's disease, it is preceded by a long period of deficits in the connectivity of the ...
Orly, Lazarov, Carolyn, Hollands
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Impact of pediatric traumatic brain injury on hippocampal neurogenesis
Neural Regeneration Research, 2021 Traumatic brain injury (TBI) is a major cause of mortality and morbidity in the pediatric population. With advances in medical care, the mortality rate of pediatric TBI has declined.
Mariam Rizk, Justin Vu, Zhi Zhang
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Serotonin and Hippocampal Neurogenesis [PDF]
Neuropsychopharmacology, 1999 The dentate gyrus continues to produce new granule neurons well into adulthood. This has been demonstrated for many mammalian species, from rodents to primates. The proliferation of granule cell precursors can be suppressed by stressful experiences, presumably via adrenal steroids.
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Disruption of the Microglial ADP Receptor P2Y13 Enhances Adult Hippocampal Neurogenesis
Frontiers in Cellular Neuroscience, 2018 In mammalian species, including humans, the hippocampal dentate gyrus (DG) is a primary region of adult neurogenesis. Aberrant adult hippocampal neurogenesis is associated with neurological pathologies.
Jennifer Stefani +10 more
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Enhancement of Hippocampal Neurogenesis by Lithium [PDF]
Journal of Neurochemistry, 2000 Abstract: Increasing evidence suggests that mood disorders are associated with a reduction in regional CNS volume and neuronal and glial cell atrophy or loss. Lithium, a mainstay in the treatment of mood disorders, has recently been demonstrated to robustly increase the levels of the cytoprotective B‐cell lymphoma protein‐2 (bcl‐2) in areas of rodent ...
G, Chen +4 more
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Impact of treadmill running and sex on hippocampal neurogenesis in the mouse model of amyotrophic lateral sclerosis. [PDF]
PLoS ONE, 2012 Hippocampal neurogenesis in the subgranular zone (SGZ) of dentate gyrus (DG) occurs throughout life and is regulated by pathological and physiological processes.
Xiaoxing Ma +4 more
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Reconsidering hippocampal neurogenesis in Alzheimer's disease [PDF]
Frontiers in Neuroscience, 2014 Hippocampal neurogenesis is oftenthought to be necessary to maintainhippocampus-dependent cognitive abil-ities (see references in Deng et al., 2010).Most investigations using transgenic ani-mal models of Alzheimer’s disease (AD)report a reduction in hippocampal neu-rogenesis (see references in Mu and Gage,2011) giving rise to the idea that ...
Alonso eMartinez-Canabal +1 more
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Bacterial Meningitis Impairs Hippocampal Neurogenesis [PDF]
Journal of Neuropathology & Experimental Neurology, 2011 Bacterial meningitis causes persisting neurofunctional sequelae. Theoccurrence of apoptotic cell death in the hippocampal subgranular zone of the dentate gyrus characterizes the disease in patients and relates to deficits in learning and memory in corresponding experimental models.
Hofer S +4 more
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IBRO Neuroscience Reports, 2022 Norepinephrine (NE), and specific adrenoceptors, have been reported to influence distinct aspects of adult hippocampal neurogenesis, including latent stem cell activation, progenitor proliferation, and differentiation.
Darshana Kapri +9 more
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