Results 31 to 40 of about 152,418 (295)

Role of adult hippocampal neurogenesis in stress resilience

open access: yesNeurobiology of Stress, 2015
There is a growing appreciation that adult hippocampal neurogenesis plays a role in emotional and cognitive processes related to psychiatric disorders. Although many studies have investigated the effects of stress on adult hippocampal neurogenesis, most ...
Brunno R. Levone   +2 more
doaj   +1 more source

Signaling in adult neurogenesis [PDF]

open access: yesCurrent Opinion in Neurobiology, 2010
Neural stem cells (NSCs) in the adult brain continuously supply new neurons to the hippocampal dentate gyrus (DG) and the olfactory bulb (OB). Recent studies indicate that the progression from neural precursor cells (NPCs) to mature neurons is tightly controlled by coordinate cell-intrinsic programs and external signals within the neurogenic niche.
Yangling, Mu, Star W, Lee, Fred H, Gage
openaire   +2 more sources

Dopamine and adult neurogenesis [PDF]

open access: yesJournal of Neurochemistry, 2006
AbstractDopamine is an important neurotransmitter implicated in the regulation of mood, motivation and movement. We have reviewed here recent data suggesting that dopamine, in addition to being a neurotransmitter, also plays a role in the regulation of endogenous neurogenesis in the adult mammalian brain. In addition, we approach a highly controversial
Andreas, Borta, Günter U, Höglinger
openaire   +2 more sources

Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]

open access: yes, 2020
Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
core   +1 more source

Genetic Methods to Identify and Manipulate Newly born Neurons in the Adult Brain

open access: yesFrontiers in Neuroscience, 2011
Although mammalian neurogenesis is mostly completed by the perinatal period, new neurons are continuously generated in the subventricular zone of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus.
Itaru eImayoshi   +2 more
doaj   +1 more source

Neurogenesis in zebrafish – from embryo to adult [PDF]

open access: yes, 2013
Neurogenesis in the developing central nervous system consists of the induction and proliferation of neural progenitor cells and their subsequent differentiation into mature neurons. External as well as internal cues orchestrate neurogenesis in a precise
Rebecca Schmidt   +2 more
core   +2 more sources

Adult Olfactory Bulb Neurogenesis [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2016
Most organisms use their olfactory system to detect and analyze chemical cues from the external world to guide essential behaviors. From worms to vertebrates, chemicals are detected by odorant receptors expressed by olfactory sensory neurons, which in vertebrates send an axon to the primary processing center called the olfactory bulb (OB).
Pierre-Marie, Lledo, Matt, Valley
openaire   +2 more sources

Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain. [PDF]

open access: yes, 2018
Restoring adult stem cell function provides an exciting approach for rejuvenating the aging brain. However, molecular mechanisms mediating neurogenic rejuvenation remain elusive.
Bieri, Gregor   +6 more
core   +2 more sources

Adiponectin Mediates Running-Restored Hippocampal Neurogenesis in Streptozotocin-Induced Type 1 Diabetes in Mice

open access: yesFrontiers in Neuroscience, 2018
Streptozotocin (STZ)-induced diabetes impairs learning and memory performance and reduces adult hippocampal neurogenesis. Physical exercise brings beneficial effects.
Suk-Yu Yau   +8 more
doaj   +1 more source

Spatially regulated adult neurogenesis [PDF]

open access: yesAnnals of Neurosciences, 2013
Adult neurogenesis has been the center of attention for decades. Neuroscientists hope to understand the mechanism underlying this phenomenon that might provide a unique perception of brain repair in future. Neurogenesis is referred to the process in which neuronal stem cells and progenitors generate new neurons in non-pathologic setting. Although there
Rikani, Azadeh A.   +5 more
openaire   +2 more sources

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