Results 31 to 40 of about 152,418 (295)
Role of adult hippocampal neurogenesis in stress resilience
There is a growing appreciation that adult hippocampal neurogenesis plays a role in emotional and cognitive processes related to psychiatric disorders. Although many studies have investigated the effects of stress on adult hippocampal neurogenesis, most ...
Brunno R. Levone +2 more
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Signaling in adult neurogenesis [PDF]
Neural stem cells (NSCs) in the adult brain continuously supply new neurons to the hippocampal dentate gyrus (DG) and the olfactory bulb (OB). Recent studies indicate that the progression from neural precursor cells (NPCs) to mature neurons is tightly controlled by coordinate cell-intrinsic programs and external signals within the neurogenic niche.
Yangling, Mu, Star W, Lee, Fred H, Gage
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Dopamine and adult neurogenesis [PDF]
AbstractDopamine is an important neurotransmitter implicated in the regulation of mood, motivation and movement. We have reviewed here recent data suggesting that dopamine, in addition to being a neurotransmitter, also plays a role in the regulation of endogenous neurogenesis in the adult mammalian brain. In addition, we approach a highly controversial
Andreas, Borta, Günter U, Höglinger
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Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]
Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
core +1 more source
Genetic Methods to Identify and Manipulate Newly born Neurons in the Adult Brain
Although mammalian neurogenesis is mostly completed by the perinatal period, new neurons are continuously generated in the subventricular zone of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus.
Itaru eImayoshi +2 more
doaj +1 more source
Neurogenesis in zebrafish – from embryo to adult [PDF]
Neurogenesis in the developing central nervous system consists of the induction and proliferation of neural progenitor cells and their subsequent differentiation into mature neurons. External as well as internal cues orchestrate neurogenesis in a precise
Rebecca Schmidt +2 more
core +2 more sources
Adult Olfactory Bulb Neurogenesis [PDF]
Most organisms use their olfactory system to detect and analyze chemical cues from the external world to guide essential behaviors. From worms to vertebrates, chemicals are detected by odorant receptors expressed by olfactory sensory neurons, which in vertebrates send an axon to the primary processing center called the olfactory bulb (OB).
Pierre-Marie, Lledo, Matt, Valley
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Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain. [PDF]
Restoring adult stem cell function provides an exciting approach for rejuvenating the aging brain. However, molecular mechanisms mediating neurogenic rejuvenation remain elusive.
Bieri, Gregor +6 more
core +2 more sources
Streptozotocin (STZ)-induced diabetes impairs learning and memory performance and reduces adult hippocampal neurogenesis. Physical exercise brings beneficial effects.
Suk-Yu Yau +8 more
doaj +1 more source
Spatially regulated adult neurogenesis [PDF]
Adult neurogenesis has been the center of attention for decades. Neuroscientists hope to understand the mechanism underlying this phenomenon that might provide a unique perception of brain repair in future. Neurogenesis is referred to the process in which neuronal stem cells and progenitors generate new neurons in non-pathologic setting. Although there
Rikani, Azadeh A. +5 more
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