Results 11 to 20 of about 163,501 (312)
Adult Neurogenesis in Drosophila [PDF]
Cell Reports, 2013 Adult neurogenesis has been linked to several cognitive functions and neurological disorders. Description of adult neurogenesis in a model organism like Drosophila could facilitate the genetic study of normal and abnormal neurogenesis in the adult brain.
Fernández-Hernández Ismael +2 more
openaire +7 more sources
Cells, 2022 One of the most intriguing dogmas in neurosciences—the empirical lack of brain neuronal regeneration in adulthood onwards to late life—began to be debunked initially by research groups focused on understanding postnatal (early days/weeks of murine and guinea pigs) neurodevelopmental and neuroplastic events [...]
Andreia Vaz, Inês Ribeiro, Luísa Pinto
openaire +3 more sources
Neurogenesis or non-neurogenesis: that is the question [PDF]
Journal of Clinical Investigation, 2014 Neural stem/precursor cells (NPCs) that reside within germinal niches of the adult CNS have more complex roles than previously expected. In addition to their well-documented neurogenic functions, emerging evidence indicates that NPCs exert non-neurogenic functions that contribute to the regulation and preservation of tissue homeostasis under both ...
MARTINO , GIANVITO +2 more
openaire +3 more sources
Neurogenesis and Epilepsy [PDF]
Epilepsia, 2010 Abstract Medial temporal lobe epilepsy (mTLE) is a common and often intractable form of epilepsy. Approximately 50 million people suffer from different epilepsies worldwide,1 30%–40% of whom may continue to have poorly controlled seizures despite therapy.2,3 Medial TLE is estimated to be the most common cause of intractable epilepsy in ...
Parent, Jack M., Kron, Michelle M.
openaire +3 more sources
Metabolism and neurogenesis [PDF]
Current Opinion in Neurobiology, 2017 The generation of neurons in the developing and adult mammalian brain by neural stem/progenitor cells (NSPCs) depends on a tight control of NSPC activity and neuronal differentiation that is regulated by a plethora of intrinsic and extrinsic molecular cues.
Knobloch, Marlen, Jessberger, Sebastian
openaire +4 more sources
Development, 2014 A unique feature of humans is the complexity of our central nervous system. A fully functional brain requires that billions of neurons make specific contacts in a highly coordinated way, an issue that is still not well understood. The neural retina constitutes an excellent system with which to analyze key aspects of neurogenesis and circuit formation ...
Lázaro, Centanin, Joachim, Wittbrodt
openaire +2 more sources
Appetite for Neurogenesis [PDF]
Developmental Cell, 2017 Adult neural stem cells (NSCs) in the ventricular-subventricular zone (V-SVZ) produce diverse olfactory bulb (OB) neurons. In a recent paper in Science, Paul et al. (2017) show that hypothalamic propiomelanocortin (POMC) neurons innervate the anterior ventral V-SVZ and regulate deep granule interneuron production depending on feeding behavior.
Kristen L, Zuloaga, Sally, Temple
openaire +2 more sources
RNA-binding protein signaling in adult neurogenesis [PDF]
, 2022 The process of neurogenesis in the brain, including cell proliferation, differentiation, survival, and maturation, results in the formation of new functional neurons.
Wui-Man, Lau Benson +5 more
core +1 more source
Neuron’s little helper: the role of primary cilia in neurogenesis [PDF]
, 2019 The generation of new neurons involves a great variety of cell-extrinsic and cell-intrinsic signals. The primary cilium, long regarded as an “evolutionary vestige,” has emerged as an essential signaling hub in many cells, including neural progenitors and
Badano, José L. +2 more
core +3 more sources
Absent or low rate of adult neurogenesis in the hippocampus of bats (Chiroptera) [PDF]
, 2007 Bats are the only flying mammals and have well developed navigation abilities for 3D-space. Even bats with comparatively small home ranges cover much larger territories than rodents, and long-distance migration by some species is unique among small ...
Winter, Y +19 more
core +1 more source