Results 41 to 50 of about 177,971 (301)

RNA-binding protein signaling in adult neurogenesis

open access: yes, 2022
The process of neurogenesis in the brain, including cell proliferation, differentiation, survival, and maturation, results in the formation of new functional neurons.
Wui-Man, Lau Benson   +5 more
core   +1 more source

Human Amniotic Fluid Cells Form Functional Gap Junctions with Cortical Cells

open access: yesStem Cells International, 2012
The usage of stem cells is a promising strategy for the repair of damaged tissue in the injured brain. Recently, amniotic fluid (AF) cells have received a lot of attention as an alternative source of stem cells for cell-based therapies.
Anna Jezierski   +6 more
doaj   +1 more source

Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition

open access: yesNature Communications, 2023
Within the chromatin, distal elements interact with promoters to regulate specific transcriptional programs. Histone acetylation, interfering with the net charges of the nucleosomes, is a key player in this regulation.
Mattia Zaghi   +22 more
doaj   +1 more source

The dangers of rubella virus

open access: yeseLife, 2023
The rubella virus can interfere with fetal brain development by infecting immune cells called microglia during pregnancy.
Ekaterina Epifanova, Laurent Nguyen
doaj   +1 more source

Generation of adult hippocampal neural stem cells occurs in the early postnatal dentate gyrus and depends on cyclin D2

open access: yesThe EMBO Journal, 2023
Lifelong hippocampal neurogenesis is maintained by a pool of multipotent adult neural stem cells (aNSCs) residing in the subgranular zone of the dentate gyrus (DG).
Oier Pastor-Alonso   +11 more
doaj   +1 more source

Epilepsy and Adult Neurogenesis [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2015
Seizure activity in the hippocampal region strongly affects stem cell-associated plasticity in the adult dentate gyrus. Here, we describe how seizures in rodent models of mesial temporal lobe epilepsy (mTLE) affect multiple steps in the developmental course from the dividing neural stem cell to the migrating and integrating newborn neuron. Furthermore,
Jessberger, Sebastian, Parent, Jack M
openaire   +3 more sources

Astrocyte-secreted GDNF and glutathione antioxidant system protect neurons against 6OHDA cytotoxicity

open access: yesNeurobiology of Disease, 2009
In recent years, GDNF has emerged as a protective and restorative agent in several models of neurodegeneration; however, the exact molecular mechanisms responsible for these effects are not yet fully understood. Here we examined the effects of astrocytes
Jagdeep K. Sandhu   +8 more
doaj   +1 more source

Adult Neural Stem Cell Regulation by Small Non-coding RNAs: Physiological Significance and Pathological Implications

open access: yesFrontiers in Cellular Neuroscience, 2022
The adult neurogenic niches are complex multicellular systems, receiving regulatory input from a multitude of intracellular, juxtacrine, and paracrine signals and biological pathways. Within the niches, adult neural stem cells (aNSCs) generate astrocytic
Amber Penning   +7 more
doaj   +1 more source

Does the plasticity of neural stem cells and neurogenesis make them biosensors of disease and damage?

open access: yesFrontiers in Neuroscience, 2022
Postnatal and adult neurogenesis takes place in the dentate gyrus of the hippocampus in the vast majority of mammals due to the persistence of a population of neural stem cells (NSCs) that also generate astrocytes and more NSCs.
Ane Rodríguez-Bodero   +4 more
doaj   +1 more source

Effect of Exercise on Adult Neurogenesis in Crayfish [PDF]

open access: yes, 2012
Adult neurogenesis, formation of new neurons, has been determined to be a part of the normal physiology in all species of animals studied to date. There have been several factors observed to increase the number of newly formed cells; the most potent of ...
Klutts, Jennifer E.
core  

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