Results 61 to 70 of about 163,501 (312)
Neural Plasticity, 2018 Neurogenesis in the hippocampus is influenced by several factors including external stimuli. In addition to their involvement in learning and memory processes, newborn neurons of the dentate gyrus (DG) buffer against the effects of stress.
Gerardo Bernabé Ramírez-Rodríguez +2 more
doaj +1 more source
Advanced Materials Interfaces, EarlyView.Polyelectrolyte scaffold coatings modified with Cu and Fe3O4 nanoparticles regulate neural stem cell behavior in vitro. Increased Fe3O4 content enhances mitochondrial activity and neuronal differentiation, whereas higher Cu levels reduce cell viability.
Anna Grzeczkowicz +5 more
wiley +1 more source
Molecular Mechanism of Adult Neurogenesis and its Association with Human Brain Diseases [PDF]
, 2016 Recent advances in neuroscience challenge the old dogma that neurogenesis occurs only during embryonic development. Mounting evidence suggests that functional neurogenesis occurs throughout adulthood.
Ni Song, He Liu
core +1 more source
Regulation of Injury-Induced Neurogenesis by Nitric Oxide
Stem Cells International, 2012 The finding that neural stem cells (NSCs) are able to divide, migrate, and differentiate into several cellular types in the adult brain raised a new hope for restorative neurology.
Bruno P. Carreira +2 more
doaj +1 more source
Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Advanced Science, EarlyView.Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
The effects of housing conditions on neurogenesis in the black-capped chickadee [PDF]
, 2014 Black-capped chickadees (Poecile atricapillus) store and retrieve thousands of seeds during the fall and winter, seemingly in anticipation of reduced resource availability coinciding with onset of harsh weather, and laboratory experiments have confirmed ...
Aitken, Sean
core
Effects of amphetamine administration on neurogenesis in adult rats [PDF]
, 2017 In our study expression of phospho-(Ser-10)-histone H3 (pH3S10), a marker for the early stage of neurogenesis, and cellular early response genes were investigated using c-Fos protein as an example of a transcription factor in the neurogenic process in ...
Tomasz Stępień +4 more
core +1 more source
HB-EGF activates EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures
Life Science AllianceBlocking epidermal growth factor receptor signaling after seizures prevents the induction of reactive neural stem cells and preserves neurogenesis in the hippocampus of mice.
Oier Pastor-Alonso +7 more
doaj +1 more source
Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs
Cell Reports, 2016 Spinocerebellar ataxia type 6 (SCA6) is a dominantly inherited neurodegenerative disease characterized by loss of Purkinje cells in the cerebellum. SCA6 is caused by CAG trinucleotide repeat expansion in CACNA1A, which encodes Cav2.1, α1A subunit of P/Q ...
Yoshihito Ishida +6 more
doaj +1 more source
Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome
Frontiers in Cell and Developmental Biology, 2020 Hippocampal neurogenesis, the process by which neural stem cells (NSCs) continuously generate new neurons in the dentate gyrus (DG) of most mammals including humans, is chiefly regulated by neuronal activity.
Soraya Martín-Suárez +6 more
doaj +1 more source