Results 251 to 260 of about 110,453 (370)

Loss of NFIA Impairs Adult Hippocampal Neurogenesis. [PDF]

Hippocampus
Wang M, van Bruggen R, Mohammed L, Egor K, Tan Q.   +4 more
europepmc   +1 more source

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

Science, 2009
C. Clelland, M. Choi, C. Romberg, G. Clemenson, A. Fragniere, P. Tyers, S. Jessberger, L. Saksida, R. Barker, F. Gage, T. Bussey   +10 more
semanticscholar   +1 more source

Hydrogen‐Mediated Activation of the Nrf2/HO‐1 Signaling Pathway Improves Cognitive Impairment in Sleep‐Deprived Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Hydrogen enhances memory and learning capabilities in sleep‐deprived mice by activating the Nrf2/HO‐1 signaling pathway, while suppressing neuronal damage, oxidative stress, and inflammatory responses. ABSTRACT Aims This study investigated the effects of hydrogen (H2) on cognitive impairment in sleep‐deprived mice mediated by the nuclear factor ...
QiFan Xiao, ShiRui Zhou, Bin Tang, YuQing Zhu   +3 more
wiley   +1 more source

Adult hippocampal neurogenesis: New avenues for treatment of brain disorders. [PDF]

Stem Cell Reports
Chen L, Li Z, Wang W, Zhou Y, Li W, Wang Y.   +5 more
europepmc   +1 more source

β‐Asarone Attenuates Neuroinflammation of Alzheimer's Disease by Activating Autophagy and Suppressing NLRP3 Inflammasome Assembly

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
β‐amyloid activates microglia via the TLR/NF‐κB pathway and primes the NLRP3 inflammasome, driving neuroinflammation. β‐asarone counteracts this by activating autophagy, which degrades NLRP3 components and inhibits inflammasome assembly. This reduces IL‐1β maturation, suppresses cytokine release, and alleviates neuronal damage and cognitive deficits in
Zhiwei Xu, Wanying Xu, Jinxin He, Jiahui Qian, Hui Wang, Changyu Li, Xiaojie Zhou   +6 more
wiley   +1 more source

Neuronal deletion of phosphatase and tensin homolog in mice results in spatial dysregulation of adult hippocampal neurogenesis. [PDF]

Front Mol Neurosci, 2023
Latchney SE, Ruiz Lopez BR, Womble PD, Blandin KJ, Lugo JN.   +4 more
europepmc   +1 more source

Response to Comment on “Impact of neurodegenerative diseases on human adult hippocampal neurogenesis”

, 2022
Julia Terreros‐Roncal, Elena P. Moreno‐Jiménez, Miguel Flor‐García, C. B. Rodríguez-Moreno, Mariela F. Trinchero, Berenice Márquez‐Valadez, Fabio Cafini, Alberto Rábano, María Llorens‐Martín   +8 more
openalex   +2 more sources

Ablation of Unilateral Hippocampal GABAergic Neurons: A Novel Mouse Model of Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
A novel mouse model of mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS) by unilateral, partial ablation of hippocampal GABAergic neurons is established. The model recapitulates key features of the human condition, including spontaneous recurrent seizures, HS‐like pathology, and associated cognitive deficits.
Ting Tang, Jinkun Xu, Bin Fu, Chao Geng, Yuhao Li, Yuying Qi, Changkai Hou, Junping He, Yihe Wang, Yumin Luo, Guoguang Zhao   +10 more
wiley   +1 more source

Modulation of adult hippocampal neurogenesis by interleukin 1 signaling. [PDF]

Neurobiol Sleep Circadian Rhythms
Smirnova MI, Quan N.
europepmc   +1 more source

Simvastatin Promotes Adult Hippocampal Neurogenesis by Enhancing Wnt/β-Catenin Signaling [PDF]

, 2013
Nicholas Robin, Zsuzsa Agoston, Travis L. Biechele, Richard G. James, Jason D. Berndt, Randall T. Moon   +5 more
openalex   +1 more source