Results 261 to 270 of about 110,453 (370)

Aerobic Exercise Promotes Hippocampal Neurogenesis and Ameliorates Cognitive Dysfunction Induced by Unilateral Labyrinthectomy

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
UL induced significant spatial and non‐spatial cognitive dysfunction and hippocampal neurogenesis inhibition, whereas aerobic exercise intervention effectively reversed these impairments. Transcriptomic profiling and pharmacological evidence identified MHC class I/II–related pathways (H2‐K1, H2‐Eb1, CD74) as key mediators of the restorative effects of ...
Zhanghong Zhou, Xixi Yu, E. Tian, Zhaoqi Guo, Jingyu Chen, Jiaqi Guo, Shiyu Shi, Wandi Xu, Ni Zhai, Caijuan Qiao, Yuejin Zhang, Jun Wang, Yisheng Lu, Sulin Zhang   +13 more
wiley   +1 more source

Orphan Receptor GPRC5B Controls Adult Hippocampal Neurogenesis and Affects Retinoic Acid-Mediated Behaviors. [PDF]

Mol Neurobiol
Fu W, Alabdali R, Mousaei A, Daher F, Wettschureck N, MacLean DM, Fogaça MV, Orlandi C.   +7 more
europepmc   +1 more source

Multitype Bellman-Harris branching model provides biological predictors of early stages of adult hippocampal neurogenesis [PDF]

, 2017
Biao Li, Amanda Sierra, Juan J. P. Deudero, Fatih Semerci, Andrew Laitman, Marek Kimmel, Mirjana Maletić‐Savatić   +6 more
openalex   +1 more source

Low‐Intensity Pulsed Ultrasound Alleviation of LPS‐Induced Depression‐Like Behavior via Microglial P2X4R Inhibition and BDNF/TrkB Pathway Activation

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
LIPUS alleviates LPS‐induced depressive‐like behavior by suppressing microglial P2X4R in the hippocampus. P2X4R downregulation restores BDNF/TrkB signaling, thereby reducing microglial activation, pro‐inflammatory cytokine release, and neuronal apoptosis.
Yuanli Wang, Xinyue Meng, Xinyi Zhang, Ruilin Chen, Mianzhi Zhang, Deli Yang, Wanke Zou, Paul K. Chu, Chengbiao Ding, Hongrui Zhan   +9 more
wiley   +1 more source

FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice. [PDF]

Int J Mol Sci, 2022
Wang J, Zhai HR, Ma SF, Shi HZ, Zhang WJ, Yun Q, Liu WJ, Liu ZZ, Zhang WN.   +8 more
europepmc   +1 more source

Rasal1: A candidate exercise mimetic to increase adult hippocampal neurogenesis in middle age [PDF]

Yvonne M. Nolan, Maria Giovanna Caruso, Sebastian Dohm-Hansen, Sarah Nicolas, Jane A English, Aonghus Lavelle, Paul Lucassen, Joram D. Mul, Olivia O'Leary   +8 more
openalex   +1 more source

Gut microbiota and central nervous system's direct bidirectional regulation: The mechanisms of the gut–brain axis in irritable bowel syndrome

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Gut microbiota directly modulates central nervous system activity via vagal, sympathetic and sensory neural circuits. Brainstem nuclei integrate microbial signals to regulate gut motility, secretion and visceral sensitivity. DRG neurons and stress‐responsive pathways link microbial cues to host defence and epithelial homeostasis. Dysregulated gut–brain
Jinxia Zhai, Yingjie Li, Jiameng Liu, Cong Dai   +3 more
wiley   +1 more source

The 5:2 diet does not increase adult hippocampal neurogenesis or enhance spatial memory in mice. [PDF]

EMBO Rep, 2023
Roberts LD, Hornsby AK, Thomas A, Sassi M, Kinzett A, Hsiao N, David BR, Good M, Wells T, Davies JS.   +9 more
europepmc   +1 more source

Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain

Developmental Dynamics, Volume 255, Issue 2, Page 187-208, February 2026.
Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina, Lizbeth A. Bolaños Castro, Juan Sebastian Eguiguren, Sara Zocher, Anne Karasinsky, Dimitri Widmer, Alexandre Espinós, Victor Borrell, Michael Brand, Kyoko Miura, Oliver Zierau, Maximina H. Yun, Tomohisa Toda   +12 more
wiley   +1 more source

Inactive but awake behaviour as indicating a depression-like state in mice: aetiological factors and association with adult hippocampal neurogenesis. [PDF]

R Soc Open Sci
Trevarthen A, Davy R, Finnegan E, Railton RL, Paul E, Mendl M, Smulders T, Fureix C.   +7 more
europepmc   +1 more source