Results 291 to 300 of about 110,453 (370)

Brain Resident Ly6C^hi Monocytes Are Necessary for Maintaining Adult Hippocampal Neurogenesis. [PDF]

Aging Dis
Huang Y, Gao N, Liu B, Luo W, Chen J, Chen Y, Bi Y, Zhou Z.   +7 more
europepmc   +1 more source

Differential roles of TNFR1 and TNFR2 signaling in adult hippocampal neurogenesis

, 2013
Zhiguo Chen, Theo D. Palmer
openalex   +2 more sources

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan, Eva Troyano‐Rodriguez, Jennifer Ihuoma, Sharon Negri, Rakesh Rudraboina, Aleksandra Kosmider, Shantipriya Awasthi, Priya Balasubramanian, Shannon Conley, Andriy Yabluchanskiy, Anna Csiszar, Zoltan Ungvari, Rafael de Cabo, Stefano Tarantini   +13 more
wiley   +1 more source

The relationship between adult hippocampal neurogenesis and cognitive impairment in Alzheimer's disease. [PDF]

Alzheimers Dement
Geigenmüller JN, Tari AR, Wisloff U, Walker TL.   +3 more
europepmc   +1 more source

Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss

Aging Cell, Volume 25, Issue 2, February 2026.
Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli, Lucía Casares‐Crespo, Elena Juárez‐Escoto, Helena Mira   +3 more
wiley   +1 more source

Periodic Therapeutic Phlebotomy Mitigates Systemic Aging Phenotypes by Promoting Bone Marrow Function

Aging Cell, Volume 25, Issue 2, February 2026.
In D‐galactose‐induced aging model, periodic therapeutic phlebotomy exerts significant and comprehensive anti‐aging effects by inducing bone marrow microenvironment restoration, which rebalances hematopoiesis to restore peripheral blood function and ameliorate systemic aging phenotypes.
Ji‐Ru Cai, Jian Zhang, Yue‐Xin Ning, Jing Zhang, Tian‐Ce Xu, Mei‐Chen Liu, Ke‐Xin Wang, Hui‐Sheng Chen   +7 more
wiley   +1 more source

Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Male Mice. [PDF]

Biol Psychiatry Glob Open Sci
Chang WL, Tegang K, Samuels BA, Saxe M, Wichmann J, David DJ, David IM, Augustin A, Fischer H, Golling S, Lamerz J, Roth D, Graf M, Zoffmann S, Santarelli L, Jagasia R, Hen R.   +16 more
europepmc   +1 more source

Adipose‐Specific GHR Deletion Attenuates Brain Aging and Cognitive Decline in Aged Mice

Aging Cell, Volume 25, Issue 2, February 2026.
Adipose GHR deletion counteracts brain aging and cognitive decline in aged mice. This identifies adipose GH signaling as a peripheral regulator of neuroprotection and cognition. ABSTRACT Brain aging is marked by neuronal loss, synaptic deterioration, neuroinflammation, and proteinopathies, all of which contribute to cognitive decline. Although systemic
Yue Zhang, Rui Ma, Jia He, Liyuan Ran, Xuewei Yang, Yue Xi, Yingjie Wu   +6 more
wiley   +1 more source

Mapping the current trends and hotspots of adult hippocampal neurogenesis from 2004-2023: a bibliometric analysis. [PDF]

Front Neurosci
Liu Y, Zhang J, Gu X, Jia S.
europepmc   +1 more source

Association Between Metabolic Syndrome, Obesity, and Cognitive Performances in Individuals With Bipolar Disorders: Cross‐Sectional and Longitudinal Analyses in the FACE‐BD Cohort

Acta Psychiatrica Scandinavica, Volume 153, Issue 2, Page 108-121, February 2026.
ABSTRACT Introduction Metabolic syndrome (MetS) has been suggested to be associated with cognitive impairments in bipolar disorder (BD); however, studies are limited by small sample sizes or cross‐sectional design. Our objective is to evaluate the cross‐sectional and longitudinal associations between MetS and cognitive performances in a large cohort of
I. Palimaru, B. Etain, M. Leboyer, Y. Dansou, P. Favre, S. Gard, V. Aubin, F. Bellivier, R. Belzeaux, P. Courtet, C. Dubertret, E. Haffen, A. Lefrere, P. M. Llorca, E. Olié, M. Polosan, L. Samalin, R. Schwan, the FondaMental Academic Centers of Expertise in Bipolar Disorders (FACE‐BD) Collaborators, B. Etain, E. Olié, M. Leboyer, E. Haffen, P. M. Llorca, V. Barteau, S. Bensalem, O. Godin, H. Laouamri, K. Souryis, S. Hotier, A. Pelletier, F. Hergeta, J. Petrucci, L. Willaume, F. Bellivier, B. Etain, V. Hennion, E. Marlinge, J. Meheust, A. Richard, M. Carminati, H. Francisque, S. Gard, K. M’Bailara, C. Elkael, F. Hoorelbeke, I. Minois, J. Sportich, N. Da Ros, C. Dubertret, N. Mazer, C. Portalier, C. Scognamiglio, A. Bing, P. Laurent, L. Boukhobza, P. Courtet, S. Denat, B. Deffinis, D. Ducasse, M. Gachet, A. Lengvenyté, F. Molière, L. Nass, E. Olié, G. Tarquini, A. Lefrere, E. Moreau, J. Pastol, F. Groppi, H. Polomeni, J. Bauberg, L. Lescalier, I. Muraccioli, A. Suray, R. Cohen, J. P. Kahn, M. Milazzo, O. Wajsbrot‐Elgrabli, T. Bougerol, A. Pouchon, A. Bertrand, B. Fredembach, A. Suisse, Q. Denoual, M. Polosan, A. M. Galliot, L. Brehon, G. Bonny, L. Durand, V. Feuga, N. Kayser, P. Roux, V. Aubin, I. Cussac, M. A. Dupont, J. Loftus, I. Medecin, C. Dubertret, N. Mazer, P. Laurent, L. Samalin, P. M. Llorca, M. Mennetrier, T. Bonnet, D. Lacelle, M. Vayssié, C. Beal, O. Blanc, P. Roux, O. Godin   +110 more
wiley   +1 more source