Results 331 to 340 of about 110,453 (370)
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Glia, 2020
Neuroinflammation driven by interferon‐gamma (IFN‐γ) and microglial activation has been linked to neurological disease. However, the effects of IFN‐γ‐activated microglia on hippocampal neurogenesis and behavior are unclear.
Jinqiang Zhang +10 more
semanticscholar +1 more source
Neuroinflammation driven by interferon‐gamma (IFN‐γ) and microglial activation has been linked to neurological disease. However, the effects of IFN‐γ‐activated microglia on hippocampal neurogenesis and behavior are unclear.
Jinqiang Zhang +10 more
semanticscholar +1 more source
GABAergic Regulation of Adult Hippocampal Neurogenesis
Molecular Neurobiology, 2016Adult hippocampal neurogenesis has been implicated in several brain functions, including learning and memory processes. It also plays an important role in the aetiology of anxiety disorders, depression and age-related deficits. The endogenous stem cell pool is also known to hold great potential for ameliorating the diseased or aged brain.
Sibbe, Mirjam, Kulik, Akos
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Adult hippocampal neurogenesis and memory interference
Behavioural Brain Research, 2012Rats, subjected to low-dose irradiation that suppressed hippocampal neurogenesis, or a sham treatment, were administered a visual discrimination task under conditions of high, or low interference. Half of the rats engaged in running activity and the other half did not.
Gordon, Winocur +4 more
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CDK2 is Dispensable for Adult Hippocampal Neurogenesis
Cell Cycle, 2007Granule neurons of the dentate gyrus (DG) of the hippocampus undergo continuous renewal throughout life. Among cell cycle regulators, cyclin-dependent kinase 2 (Cdk2) is considered as a major regulator of S-phase entry. We used Cdk2-deficient mice to decipher the requirement of Cdk2 for the generation of new neurons in the adult hippocampus.
Vandenbosch, Renaud +10 more
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Journal of Neurotrauma, 2020
Young children who have sustained severe traumatic brain injury (TBI) can suffer from debilitating neurocognitive deficits. Impairment of adult hippocampal neurogenesis is associated with cognitive deficits and depression.
Zhi Zhang +6 more
semanticscholar +1 more source
Young children who have sustained severe traumatic brain injury (TBI) can suffer from debilitating neurocognitive deficits. Impairment of adult hippocampal neurogenesis is associated with cognitive deficits and depression.
Zhi Zhang +6 more
semanticscholar +1 more source
International Journal of Neuroscience, 2020
Molecular signalling pathways are an evolutionarily conserved multifaceted pathway that can control diverse cellular processes. The role of signalling pathways in regulating development and tissue homeostasis as well as hippocampal neurogenesis is needed
Saeid Bagheri-Mohammadi
semanticscholar +1 more source
Molecular signalling pathways are an evolutionarily conserved multifaceted pathway that can control diverse cellular processes. The role of signalling pathways in regulating development and tissue homeostasis as well as hippocampal neurogenesis is needed
Saeid Bagheri-Mohammadi
semanticscholar +1 more source
Adult Hippocampal Neurogenesis
2010Abstract In the dentate gyrus of mammals, including humans, adult hippocampal neurogenesis lifelong generates one single type of excitatory neurons, new granule cell neurons, which contribute to the mossy fiber connection between the dentate gyrus and area CA3. Adult hippocampal neurogenesis originates from a unique radial glia-like stem
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Stem Cells, 2019
We previously reported that Herpes simplex virus type‐1 (HSV‐1) infection of cultured neurons triggered intracellular accumulation of amyloid‐β protein (Aβ) markedly impinging on neuronal functions.
D. D. Li Puma +7 more
semanticscholar +1 more source
We previously reported that Herpes simplex virus type‐1 (HSV‐1) infection of cultured neurons triggered intracellular accumulation of amyloid‐β protein (Aβ) markedly impinging on neuronal functions.
D. D. Li Puma +7 more
semanticscholar +1 more source
Microenvironmental elements supporting adult hippocampal neurogenesis
Anatomical Science International, 2003Neurogenesis continues into adulthood in two distinct regions, the subventricular zone of the forebrain and the subgranular zone of the dentate gyrus. Transplantation experiments have suggested that the two neurogenic regions have a special microenvironment to support the proliferation and differentiation of stem or progenitor cells.
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Toluene inhibits hippocampal neurogenesis in adult mice
Pharmacology Biochemistry and Behavior, 2010Toluene, a representative industrial solvent and abused inhalant, decreases neuronal activity in vitro and causes mental depression and cognitive impairment in humans. However, the effects of toluene on brain function and the sites of its action are poorly understood.
Heung-Sik, Seo +9 more
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