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Neurogenesis and Hippocampal Plasticity in Adult Brain
2012Plasticity in the adult brain enables lifelong learning. The fundamental mechanism of adult neural plasticity is activity-dependent reorganization of pre-existing structure, in contrast to the widespread cellular proliferation and migration that occurs during development. Whereas adult hippocampal dentate gyrus continuously generates cohorts of neurons,
Yan, Gu, Stephen, Janoschka, Shaoyu, Ge
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Regulators of Adult Hippocampal Neurogenesis
2017One mechanism of plasticity within the adult mammalian brain is the dynamic process of adult neurogenesis that is functionally important in physiological and pathological conditions. During this process, neurons develop from adult neural stem cells (NSCs) via intermediate neural progenitors (NPCs) through several processes including proliferation ...
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Beclin1 Regulates Adult Hippocampal Neurogenesis
2015Adult neurogenesis is a process that produces neurons in the adult brain and garners potential for the development of novel therapeutic interventions to combat neurodegenerative and other brain related diseases. With the hope of increasing neurogenesis, active investigations are defining the cellular and molecular mechanisms that regulate adult neural ...
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Adult Hippocampal Neurogenesis in Major Depressive Disorder and Alzheimer's Disease.
Trends in Molecular Medicine, 2020Thomas Berger +4 more
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