Results 51 to 60 of about 179,906 (293)

Knowledge About the Human Papillomavirus Vaccine Among Employees at a Tertiary Cancer Center: Room for Improvement [PDF]

, 2020
Introduction: The human papillomavirus (HPV) vaccine is recommended by the U.S. Centers for Disease Control and Prevention for routine vaccination of boys and girls to protect against HPV-related cancers and genital warts. To meet the Healthy People 2020
Baum, George P, Bello, Rosalind S, Dahlstrom, Kristina R, DePinho, Ronald A, Hawk, Ernest, Ramondetta, Lois M, Stevens, Lori D, Sturgis, Erich M, Tamez, Elenita   +8 more
core   +2 more sources

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Knowledge, Attitude, and Practices Regarding Adult Immunization among Postgraduate Resident Doctors in MGM Hospital, Navi Mumbai, India

Journal of Public Health and Primary Care
Introduction: Adult immunization is an important but neglected health-care service. The adult population needs to keep their vaccination up to date because immunity provided through childhood vaccines weans off eventually making the adult and elderly ...
Nishank Chandrapal Kashyap, Rakesh Maruti Thamke, Aditi Tayade Singhania   +2 more
doaj   +1 more source

Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization

Cell Reports, 2020
Summary: HIV-1-infected infants develop broadly neutralizing antibodies (bnAbs) more rapidly than adults, suggesting differences in the neonatal versus adult responses to the HIV-1 envelope (Env).
Qifeng Han, Todd Bradley, Wilton B. Williams, Derek W. Cain, David C. Montefiori, Kevin O. Saunders, Robert J. Parks, Regina W. Edwards, Guido Ferrari, Olaf Mueller, Xiaoying Shen, Kevin J. Wiehe, Steven Reed, Christopher B. Fox, Wes Rountree, Nathan A. Vandergrift, Yunfei Wang, Laura L. Sutherland, Sampa Santra, M. Anthony Moody, Sallie R. Permar, Georgia D. Tomaras, Mark G. Lewis, Koen K.A. Van Rompay, Barton F. Haynes   +24 more
doaj   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

Hit the Iron When it is Red Hot [PDF]

Bengal Physician Journal, 2023
Arnab Bhattacharyya, Nilanjan De, Safikul Sarkar, Sital Chandra De   +3 more
doaj   +1 more source

Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant. [PDF]

PLoS ONE, 2008
BACKGROUND: With the exception of some live vaccines, e.g. BCG, subunit vaccines formulated with "classical" adjuvants do not induce similar responses in neonates as in adults. The usual neonatal profile is characterized by lower levels of TH1-associated
Arun T Kamath, Anne-Françoise Rochat, Mario P Valenti, Else Marie Agger, Karen Lingnau, Peter Andersen, Paul-Henri Lambert, Claire-Anne Siegrist   +7 more
doaj   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Do Primary Care Physicians Contribute to the Immunization Status of Their Adult Patients? A Story of Patients' Overconfidence Coupled With Physicians' Passivity

Frontiers in Medicine, 2021
Context: Immunization coverage counts among the priorities of public health services. To identify factors that motivate or fail to motivate patients to update their vaccination status would help to design future strategies and awareness campaigns ...
Thibaut Papis, Christine Clavien
doaj   +1 more source

Factors Associated with Immunization Opinion Leadership among Men Who Have Sex with Men in Los Angeles, California [PDF]

, 2018
We sought to identify the characteristics of men who have sex with men (MSM) who are opinion leaders on immunization issues and to identify potential opportunities to leverage their influence for vaccine promotion within MSM communities.
Bednarczyk, Robert, Fenimore, Vincent L., Frew, Paula M., Goldbeck, Cameron, Himmelstein, Rebecca, Holloway, Ian W., Lutz, Chelsea S., Randall, Laura, Tan, Diane, Wu, Elizabeth   +9 more
core   +3 more sources