Results 41 to 50 of about 1,955,835 (238)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Learning conceptions and priorities of adult engineering students in higher education

open access: yesCogent Education, 2018
The learning conceptions and priorities of adult learners in higher education institutions (HEIs) are essential to explicating the meaning adults make to teaching and learning processes as well as their knowledge and skills development. Through knowledge
Yaw Owusu-Agyeman, Magda Fourie-Malherbe
doaj   +1 more source

Access to Higher Education: the Adult Learners' Perspective [PDF]

open access: yes, 2021
Objectives This paper presents the comparison of various approaches to the issue of access to higher education for adult learners in European countries.
Duda, Ewa, Ewa Duda
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Adult Learners: Connecting Andragogy and Transformational Leadership in the Classroom [PDF]

open access: yesBusiness Ethics and Leadership
Despite the continuous progression of higher education, there is a lack of understanding of adult learners’ overall academic needs and their competing priorities.
Desiree N. Green
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Challenges Faced by Adult Learners in Online Distance Education: A Literature Review

open access: yesOpen Praxis, 2019
Although online distance education provides adult learners with an opportunity for life-long learning, there are still factors challenging them to engage in educational processes.
Mehmet Kara   +3 more
doaj   +3 more sources

Motivating Young Adult Learners in Higher Education Institutions: Experiences from Ghana

open access: yesCurrent Issues in Education
Globally, adult learners are becoming a major cohort of students pursuing degree programs in higher education institutions (IHEIs). This phenomenon could have a positive impact on productivity in the workplace if sustained in developing economies ...
Isaac Kofi Biney
doaj   +1 more source

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