ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Using adult learning characteristics and the humanities to teach undergraduate healthcare students about social determinants of health. [PDF]
Brown EA, Kinder H, Stang G, Shumpert W.
europepmc +1 more source
Circular 03/12 : audit of the use of funds : adult and community learning, former external institutions and sixth form funding in local education authorities for 2002/03 [PDF]
"This circular provides guidance to local education authorities (LEAs) on the preparation of Use of Funds statements for their adult and community learning (ACL) and former external institutions (EI) funding allocations (2002/03).
core
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Over the past decades, an increasing number of countries have decriminalized same-sex sexual acts and introduced legal protections and recognition for lesbian, gay, and bisexual (LGB)+ people.
Anna Karmann, Lisa de Vries
doaj +1 more source
Corrigendum: Optimal experience in adult learning: Conception and validation of the flow in education scale (EduFlow-2). [PDF]
Heutte J +7 more
europepmc +1 more source
Guidance for LEAs and adult education providers on the implementation of the Disability Discrimination Act Part 4 [PDF]
"This guidance is for staff in LEAs and adult education provider organisations who have responsibility for learners with learning difficulties or disabilities. The first part of the guidance gives a brief overview of the legislation and its implications
core
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
The Global Report on Adult Learning and Education (GRALE): Strengths, weaknesses and future directions. [PDF]
Boeren E, Rubenson K.
europepmc +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source

