Results 81 to 90 of about 13,262 (261)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Health utility value and its influencing factors among adult residents in Zhejiang province: a cross-sectional study using Shapley value decomposition analysis

Zhongguo gonggong weisheng
ObjectiveTo understand the health utility value and its influencing factors among adult residents in Zhejiang province, and to provide a reference for health policy formulation and evaluation.
Pinyuan DAI, Xiaoyan ZHOU, Hao WANG, Weiwei GONG, Jin PAN, Yunqi GUAN, Jieming ZHONG, Na LI   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EEG education in Brazil: a national survey of adult neurology residents

, 2022
Background: In light of the established challenges of resident EEG education worldwide, we sought to better understand the current state of neurology resident EEG education in Brazil. Objective: To define Brazilian EEG practices including in-residency
Dora Pedroso Kowacs (12686770), Elora Sampaio Lourenço (12686767), Jay Raman Gavvala (12686773), Pedro André Kowacs (5382989), Fábio Augusto NASCIMENTO (10367298)   +4 more
core   +1 more source

Prevalence of nutritional literacy and associated factors among adult residents: a cross-sectional study from marginalized Community in Islamabad, Pakistan

Frontiers in Public Health
IntroductionNutritional literacy is one of the most important and under-explored aspects of good nutritional status especially in low- and middle-income countries.ObjectiveDespite its vital role in health, nutrition literacy research, particularly in low-
Abdul Momin Rizwan Ahmad, Abdul Momin Rizwan Ahmad, Muhammad Ajmal, Zoha Imtiaz Malik, Syed Hassan Bin Usman Shah   +4 more
doaj   +1 more source

A STUDY ON EDUCATIONAL NEEDS OF ADULTS (ON THE EXAMPLE OF ZAPORIZHZHIA REGION RESIDENTS)

Advanced Education, 2018
Lifelong learning is a determining factor of the city's or region's successful socio-economic development, the development of its human potential, the basis for the regional education policy. The theoretical substantiation, development and experimental verification of the conceptual grounds of the regional education policy require a careful analysis of
Pryima, Serhii, Orlov, A., Anishchenko, O., Pozdnyakova-Kirbyateva, E.   +3 more
openaire   +5 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Total number of adult long-term and short-term residents at the colony.

, 2015
Total number of adult long-term and short-term residents at the colony.
Uma Ramakrishnan (4564), D. P. Swami Doss (707664), A. K. Vinoth Kumar (707665), Kritika M. Garg (707662), Balaji Chattopadhyay (707663), Sripathi Kandula (707666)   +5 more
core   +1 more source