Results 91 to 100 of about 13,262 (261)

EEG education in Brazil: a national survey of adult neurology residents

open access: yes, 2021
Background: In light of the established challenges of resident EEG education worldwide, we sought to better understand the current state of neurology resident EEG education in Brazil. Objective: To define Brazilian EEG practices including in-residency
Kowacs, Dora Pedroso   +9 more
core   +1 more source

Analysis of the cognitive characteristics and consumption behaviors of prepared dish consumers

open access: yesZhongguo shipin weisheng zazhi
ObjectiveTo initially understand the current status of awareness and consumption behavior of prepared dish consumers, and to provide data support for the food safety risk assessment of prepared dishes.MethodsA questionnaire survey was conducted on 600 ...
ZHU Xiaobo   +5 more
doaj   +1 more source

An epidemiological survey on prevalence of caries among adults of Yao in Liannan in Guangdong

open access: yes口腔疾病防治, 2016
Objective To explore the prevalence of caries among 35⁃44 years old adults of Yao in Liannan, North⁃ west of Guangdong, in order to provide basis for the caries prevention.
Huang You⁃feng
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Prevalence and influencing factors of comorbid chronic diseases among rural adult residents in border areas of Jilin province: a cross-sectional study

open access: yesZhongguo gonggong weisheng
ObjectiveTo understand the prevalence and influencing factors of comorbid chronic diseases among adult rural residents in the border areas of Jilin province, and to provide a reference for the prevention and control of chronic diseases among local ...
Wangen SHEN   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Impact of an Evidence-Based Medicine Workshop on Residents’ Attitudes towards and Self-Reported Ability in Evidence-Based Practice

open access: yes, 2003
Background: Evidence-based medicine (EBM) is a part of many medical school and residency curricula worldwide, but there is little research into the most effective methods to teach these skills. Purpose: To evaluate whether a course on EBM utilizing adult
Baum M.D., Karyn D.
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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